EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.14.99.66 | Adenocarcinoma |
32403054 |
Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4. |
diagnostic usage
unassigned |
3
0 |
| 1.14.99.66 | Alzheimer Disease |
33139560 |
The inhibition of LSD1 via sequestration contributes to tau-mediated neurodegeneration. |
unassigned |
0 |
| 1.14.99.66 | Breast Neoplasms |
21452019 |
Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells. |
causal interaction
therapeutic application
unassigned |
1
3
0 |
| 1.14.99.66 | Breast Neoplasms |
23000163 |
The histone demethylase LSD1 is required for estrogen-dependent S100A7 gene expression in human breast cancer cells. |
ongoing research
therapeutic application
unassigned |
4
1
0 |
| 1.14.99.66 | Breast Neoplasms |
24924415 |
Inhibition of histone demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases sensitivity to DNMT inhibitor-induced apoptosis in breast cancer cells. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
2
4
0 |
| 1.14.99.66 | Breast Neoplasms |
25679396 |
LSD1 Overexpression Is Associated with Poor Prognosis in Basal-Like Breast Cancer, and Sensitivity to PARP Inhibition. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
3
3
0 |
| 1.14.99.66 | Breast Neoplasms |
29137219 |
Functional characterization of lysine-specific demethylase 2 (LSD2/KDM1B) in breast cancer progression. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
1 |
| 1.14.99.66 | Breast Neoplasms |
30111819 |
Inhibition of histone lysine-specific demethylase 1 elicits breast tumor immunity and enhances antitumor efficacy of immune checkpoint blockade. |
diagnostic usage
therapeutic application
unassigned |
3
3
0 |
| 1.14.99.66 | Carcinogenesis |
21115810 |
Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells. |
causal interaction
ongoing research
unassigned |
2
1
0 |
| 1.14.99.66 | Carcinogenesis |
30638951 |
Significant association between KDM1A promoter hypomethylation and colorectal cancer in Han Chinese. |
diagnostic usage
ongoing research
unassigned |
4
4
0 |
