EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.14.99.38 | abc-type xenobiotic transporter deficiency |
33137324 |
P-glycoprotein deficiency enhances metabolic activation of and platelet response to clopidogrel through marked up-regulation of Cyp3a11 in mice: Direct evidence for the interplay between P-glycoprotein and Cyp3a. |
causal interaction
unassigned |
4
0 |
| 1.14.99.38 | Arthritis |
17239366 |
Effect of interleukin-6 neutralization on CYP3A11 and metallothionein-1/2 expressions in arthritic mouse liver. |
ongoing research
unassigned |
4
0 |
| 1.14.99.38 | Atherosclerosis |
28794002 |
KLF4 Regulation of Ch25h and LXR Mitigates Atherosclerosis Susceptibility. |
causal interaction
therapeutic application
unassigned |
2
1
0 |
| 1.14.99.38 | Atherosclerosis |
33193099 |
Downregulation of Cyp7a1 by Cholic Acid and Chenodeoxycholic Acid in Cyp27a1/ApoE Double Knockout Mice: Differential Cardiovascular Outcome. |
ongoing research
unassigned |
4
0 |
| 1.14.99.38 | Bacterial Infections |
29033131 |
Oxysterol Restraint of Cholesterol Synthesis Prevents AIM2 Inflammasome Activation. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
1
1
0 |
| 1.14.99.38 | Breast Neoplasms |
16381673 |
The role of pregnane x receptor in 2-acetylaminofluorene-mediated induction of drug transport and -metabolizing enzymes in mice. |
ongoing research
therapeutic application
unassigned |
3
1
0 |
| 1.14.99.38 | cholesterol 25-monooxygenase
deficiency |
29033131 |
Oxysterol Restraint of Cholesterol Synthesis Prevents AIM2 Inflammasome Activation. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
1
1
0 |
| 1.14.99.38 | Colitis |
30742043 |
The EBI2-oxysterol axis promotes the development of intestinal lymphoid structures and colitis. |
ongoing research
unassigned |
2
0 |
| 1.14.99.38 | Colitis |
31220227 |
The Oxysterol Synthesising Enzyme CH25H Contributes to the Development of Intestinal Fibrosis. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
4
1
0 |
| 1.14.99.38 | Colitis |
32859970 |
Cholesterol 25-hydroxylase protects against experimental colitis in mice by modulating epithelial gut barrier function. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
4
4
0 |
