EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.14.19.70 | Infections |
21426022 |
The Mycobacterium tuberculosis cytochromes P450: physiology, biochemistry & molecular intervention. |
diagnostic usage
ongoing research
unassigned |
1
2
0 |
| 1.14.19.70 | Tuberculosis |
11914502 |
Crystallization and preliminary crystallographic analysis of a novel cytochrome P450 from Mycobacterium tuberculosis. |
ongoing research
therapeutic application
unassigned |
3
1
0 |
| 1.14.19.70 | Tuberculosis |
12237220 |
Expression, purification and spectroscopic characterization of the cytochrome P450 CYP121 from Mycobacterium tuberculosis. |
ongoing research
therapeutic application
unassigned |
4
1
0 |
| 1.14.19.70 | Tuberculosis |
12368427 |
Azole antifungals are potent inhibitors of cytochrome P450 mono-oxygenases and bacterial growth in mycobacteria and streptomycetes. |
diagnostic usage
therapeutic application
unassigned |
2
1
0 |
| 1.14.19.70 | Tuberculosis |
12435731 |
Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 A reveals novel features of cytochrome P450. |
therapeutic application
unassigned |
1
0 |
| 1.14.19.70 | Tuberculosis |
17028183 |
Crystal structure of the Mycobacterium tuberculosis P450 CYP121-fluconazole complex reveals new azole drug-P450 binding mode. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
| 1.14.19.70 | Tuberculosis |
17073780 |
CYP121, CYP51 and associated redox systems in Mycobacterium tuberculosis: towards deconvoluting enzymology of P450 systems in a human pathogen. |
ongoing research
unassigned |
2
0 |
| 1.14.19.70 | Tuberculosis |
17553785 |
Rapid P450 heme iron reduction by laser photoexcitation of Mycobacterium tuberculosis CYP121 and CYP51B1. Analysis of CO complexation reactions and reversibility of the P450/P420 equilibrium. |
ongoing research
unassigned |
1
0 |
| 1.14.19.70 | Tuberculosis |
18089574 |
Mycobacterium tuberculosis CYP130: crystal structure, biophysical characterization, and interactions with antifungal azole drugs. |
unassigned |
0 |
| 1.14.19.70 | Tuberculosis |
18818197 |
Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv. |
ongoing research
therapeutic application
unassigned |
3
2
0 |
