EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
1.14.14.25 | Alzheimer Disease |
11698143 |
On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells. |
causal interaction ongoing research unassigned |
1 3 0 |
1.14.14.25 | Alzheimer Disease |
12123847 |
Genetic variation in the cholesterol 24-hydroxylase (CYP46) gene and the risk of Alzheimer's disease. |
causal interaction diagnostic usage unassigned |
3 3 0 |
1.14.14.25 | Alzheimer Disease |
12232784 |
Polymorphism in the cholesterol 24S-hydroxylase gene is associated with Alzheimer's disease. |
causal interaction unassigned |
4 0 |
1.14.14.25 | Alzheimer Disease |
12533083 |
Cyp46 (24S-cholesterol hydroxylase): a genetic risk factor for Alzheimer disease. |
diagnostic usage unassigned |
3 0 |
1.14.14.25 | Alzheimer Disease |
12533085 |
Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism. |
causal interaction diagnostic usage ongoing research unassigned |
1 3 2 0 |
1.14.14.25 | Alzheimer Disease |
12879635 |
[Cholesterol and statins in Alzheimer disease] |
causal interaction unassigned |
3 0 |
1.14.14.25 | Alzheimer Disease |
15034781 |
Variants of CYP46A1 may interact with age and APOE to influence CSF Abeta42 levels in Alzheimer's disease. |
causal interaction unassigned |
3 0 |
1.14.14.25 | Alzheimer Disease |
15106838 |
APOE promoter, ACE1 and CYP46 polymorphisms and beta-amyloid in Alzheimer's disease. |
causal interaction unassigned |
3 0 |
1.14.14.25 | Alzheimer Disease |
15148325 |
Differential expression of cholesterol hydroxylases in Alzheimer's disease. |
causal interaction unassigned |
2 0 |
1.14.14.25 | Alzheimer Disease |
15165699 |
Intronic CYP46 polymorphism along with ApoE genotype in sporadic Alzheimer Disease: from risk factors to disease modulators. |
diagnostic usage ongoing research unassigned |
2 1 0 |