EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
1.14.14.17 | Breast Neoplasms |
18728668 |
Squalene epoxidase, located on chromosome 8q24.1, is upregulated in 8q+ breast cancer and indicates poor clinical outcome in stage I and II disease. |
diagnostic usage ongoing research unassigned |
4 2 0 |
1.14.14.17 | Breast Neoplasms |
26777065 |
Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer. |
diagnostic usage unassigned |
3 0 |
1.14.14.17 | Breast Neoplasms |
29765154 |
The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation. |
unassigned |
0 |
1.14.14.17 | Breast Neoplasms |
33664822 |
Squalene epoxidase expression is associated with breast tumor progression and with a poor prognosis in breast cancer. |
causal interaction diagnostic usage unassigned |
4 3 0 |
1.14.14.17 | Carcinogenesis |
25787749 |
Squalene epoxidase (SQLE) promotes the growth and migration of the hepatocellular carcinoma cells. |
causal interaction diagnostic usage unassigned |
1 3 0 |
1.14.14.17 | Carcinoma |
30734525 |
Squalene epoxidase promotes the proliferation and metastasis of lung squamous cell carcinoma cells though extracellular signal-regulated kinase signaling. |
causal interaction ongoing research unassigned |
4 4 0 |
1.14.14.17 | Carcinoma |
34163246 |
High SQLE Expression and Gene Amplification Correlates with Poor Prognosis in Head and Neck Squamous Cell Carcinoma. |
diagnostic usage ongoing research unassigned |
4 1 0 |
1.14.14.17 | Carcinoma, Hepatocellular |
1964954 |
Regulation of squalene epoxidase in HepG2 cells. |
ongoing research unassigned |
4 0 |
1.14.14.17 | Carcinoma, Hepatocellular |
15581604 |
Supernatant protein factor stimulates HMG-CoA reductase in cell culture and in vitro. |
unassigned |
0 |
1.14.14.17 | Carcinoma, Hepatocellular |
15680919 |
Supernatant protein factor requires phosphorylation and interaction with Golgi to stimulate cholesterol synthesis in hepatoma cells. |
causal interaction unassigned |
1 0 |