EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.14.14.139 | 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase deficiency |
32111630 |
Bile acid composition regulates GPR119-dependent intestinal lipid sensing and food intake regulation in mice. |
causal interaction
unassigned |
1
0 |
| 1.14.14.139 | Carcinoma, Hepatocellular |
23200860 |
Disruption of Stard10 gene alters the PPAR?-mediated bile acid homeostasis. |
ongoing research
unassigned |
2
0 |
| 1.14.14.139 | Cholelithiasis |
23216301 |
Single nucleotide polymorphism rs3732860 in the 3'-untranslated region of CYP8B1 gene is associated with gallstone disease in Han Chinese. |
unassigned |
0 |
| 1.14.14.139 | Cholelithiasis |
32597704 |
Reabsorption of bile acids regulated by FXR-OATP1A2 is the main factor for the formation of cholesterol gallstone. |
unassigned |
0 |
| 1.14.14.139 | Cholestasis |
34020283 |
Effects of microplastics (MPs) and tributyltin (TBT) alone and in combination on bile acids and gut microbiota crosstalk in mice. |
unassigned |
0 |
| 1.14.14.139 | Cholestasis, Intrahepatic |
9869655 |
Differential effects of 17alpha-ethinylestradiol on the neutral and acidic pathways of bile salt synthesis in the rat. |
causal interaction
unassigned |
1
0 |
| 1.14.14.139 | cholesterol 7alpha-monooxygenase deficiency |
25447797 |
Impact of physiological levels of chenodeoxycholic acid supplementation on intestinal and hepatic bile acid and cholesterol metabolism in Cyp7a1-deficient mice. |
causal interaction
diagnostic usage
unassigned |
3
1
0 |
| 1.14.14.139 | Colorectal Neoplasms |
27341022 |
Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer. |
diagnostic usage
ongoing research
unassigned |
4
4
0 |
| 1.14.14.139 | Coronary Thrombosis |
23026663 |
New anti-platelet agents: the end of resistance? |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
1
4
0 |
| 1.14.14.139 | Diabetes Mellitus, Type 2 |
30232649 |
Rethinking Bile Acid Metabolism and Signaling for Type 2 Diabetes Treatment. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
