EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
1.13.11.24 | Breast Neoplasms |
23374458 |
High levels of ?-glutamyl hydrolase (GGH) are associated with poor prognosis and unfavorable clinical outcomes in invasive breast cancer. |
diagnostic usage ongoing research unassigned |
4 4 0 |
1.13.11.24 | Breast Neoplasms |
34262943 |
Mutational Landscape of Pirin and Elucidation of the Impact of Most Detrimental Missense Variants That Accelerate the Breast Cancer Pathways: A Computational Modelling Study. |
therapeutic application unassigned |
1 0 |
1.13.11.24 | Carcinogenesis |
33557375 |
Role of Pirin, an Oxidative Stress Sensor Protein, in Epithelial Carcinogenesis. |
causal interaction ongoing research therapeutic application unassigned |
4 3 1 0 |
1.13.11.24 | Carcinoma |
31436299 |
Curcumin decreases epithelial?mesenchymal transition by a Pirin?dependent mechanism in cervical cancer cells. |
ongoing research therapeutic application unassigned |
2 4 0 |
1.13.11.24 | Infections |
18067462 |
Quercetinase pirin makes poliovirus replication resistant to flavonoid quercetin. |
causal interaction therapeutic application unassigned |
3 2 0 |
1.13.11.24 | Lymphoma, B-Cell |
14573596 |
Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor. |
causal interaction unassigned |
1 0 |
1.13.11.24 | Melanoma |
20089166 |
Pirin delocalization in melanoma progression identified by high content immuno-detection based approaches. |
causal interaction unassigned |
1 0 |
1.13.11.24 | Melanoma |
20711196 |
A small-molecule inhibitor shows that pirin regulates migration of melanoma cells. |
causal interaction ongoing research therapeutic application unassigned |
3 1 4 0 |
1.13.11.24 | Neoplasm Metastasis |
14969819 |
Proteomics analysis of differentially expressed metastasis-associated proteins in adenoid cystic carcinoma cell lines of human salivary gland. |
causal interaction ongoing research therapeutic application unassigned |
4 3 1 0 |
1.13.11.24 | Neoplasm Metastasis |
25680527 |
Pirin regulates epithelial to mesenchymal transition independently of Bcl3-Slug signaling. |
causal interaction therapeutic application unassigned |
4 3 0 |