EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.1.1.62 | 17beta-estradiol 17-dehydrogenase deficiency |
9709959 |
Deleterious missense mutations and silent polymorphism in the human 17beta-hydroxysteroid dehydrogenase 3 gene (HSD17B3). |
causal interaction
unassigned |
4
0 |
| 1.1.1.62 | 17beta-estradiol 17-dehydrogenase deficiency |
17403431 |
Stromal cells of endometriosis fail to produce paracrine factors that induce epithelial 17beta-hydroxysteroid dehydrogenase type 2 gene and its transcriptional regulator Sp1: a mechanism for defective estradiol metabolism. |
causal interaction
unassigned |
2
0 |
| 1.1.1.62 | 17beta-estradiol 17-dehydrogenase deficiency |
32691632 |
Hydroxysteroid (17?) dehydrogenase 12 is essential for metabolic homeostasis in adult mice. |
causal interaction
unassigned |
4
0 |
| 1.1.1.62 | 3(or 17)beta-hydroxysteroid dehydrogenase deficiency |
11061520 |
3beta-hydroxysteroid dehydrogenase/delta5-->4-isomerase activity associated with the human 17beta-hydroxysteroid dehydrogenase type 2 isoform. |
causal interaction
unassigned |
2
0 |
| 1.1.1.62 | Adenocarcinoma |
29324448 |
The Expression of HSD17B12 Is Associated with COX-2 Expression and Is Increased in High-Grade Epithelial Ovarian Cancer. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
2
2
0 |
| 1.1.1.62 | Adenoma |
10199776 |
17Beta-hydroxysteroid dehydrogenase type 1, 2, 3, and 4 expression and enzyme activity in human anterior pituitary adenomas. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
3
4
1 |
| 1.1.1.62 | Adenomyosis |
16564227 |
Adenomyosis: the pathophysiology of an oestrogen-dependent disease. |
unassigned |
0 |
| 1.1.1.62 | Adrenal Insufficiency |
32904102 |
Four patients with D-bifunctional protein (DBP) deficiency: Expanding the phenotypic spectrum of a highly variable disease. |
therapeutic application
unassigned |
1
0 |
| 1.1.1.62 | Adrenocortical Carcinoma |
29383116 |
Overexpression of HSD17B4 exerts tumor suppressive function in adrenocortical carcinoma and is not associated with hormone excess. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
1
3
1 |
| 1.1.1.62 | Ataxia |
20673864 |
Mutations in the DBP-deficiency protein HSD17B4 cause ovarian dysgenesis, hearing loss, and ataxia of Perrault Syndrome. |
causal interaction
unassigned |
2
0 |
