EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.1.1.44 | Acquired Immunodeficiency Syndrome |
8809071 |
Slow-binding inhibition of 6-phosphogluconate dehydrogenase by zinc ion. |
unassigned |
0 |
| 1.1.1.44 | Anemia |
11233775 |
6-Phosphogluconate dehydrogenase deficiency in an Italian family. |
causal interaction
diagnostic usage
unassigned |
4
2
0 |
| 1.1.1.44 | Anemia, Hemolytic |
407765 |
Combined G-6PD and 6-PGD deficiency in a Hindu boy. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 1.1.1.44 | Anemia, Hemolytic |
27270429 |
Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
1
4
0 |
| 1.1.1.44 | beta-Thalassemia |
554655 |
[Aspects of the decrease of some enzyme activities in erythrocytes of subjects with beta-thalassemia] |
causal interaction
diagnostic usage
unassigned |
3
2
0 |
| 1.1.1.44 | Breast Neoplasms |
29340974 |
Inhibiting 6-phosphogluconate dehydrogenase selectively targets breast cancer through AMPK activation. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
3
4 |
| 1.1.1.44 | Breast Neoplasms |
33498665 |
Oxidative Pentose Phosphate Pathway Enzyme 6-Phosphogluconate Dehydrogenase Plays a Key Role in Breast Cancer Metabolism. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
4
4
0 |
| 1.1.1.44 | Carcinogenesis |
32801914 |
Discovery of Ebselen as an Inhibitor of 6PGD for Suppressing Tumor Growth. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
3
4
4 |
| 1.1.1.44 | Carcinogenesis |
32829780 |
6PGD Upregulation is Associated with Chemo- and Immuno-Resistance of Renal Cell Carcinoma via AMPK Signaling-Dependent NADPH-Mediated Metabolic Reprograming. |
causal interaction
unassigned |
4
0 |
| 1.1.1.44 | Carcinoma |
16634799 |
Pneumococcal 6-phosphogluconate-dehydrogenase, a putative adhesin, induces protective immune response in mice. |
ongoing research
therapeutic application
unassigned |
3
1
0 |
