EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.1.1.141 | Aberrant Crypt Foci |
16880406 |
15-Hydroxyprostaglandin dehydrogenase is an in vivo suppressor of colon tumorigenesis. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
3
2
2 |
| 1.1.1.141 | Aberrant Crypt Foci |
26476372 |
Concerted actions of ameliorated colitis, aberrant crypt foci inhibition and 15-hydroxyprostaglandin dehydrogenase induction by sonic hedgehog inhibitor led to prevention of colitis-associated cancer. |
causal interaction
therapeutic application
unassigned |
4
3
0 |
| 1.1.1.141 | Abortion, Spontaneous |
31772225 |
Early pregnancy loss in 15-hydroxyprostaglandin dehydrogenase knockout (15-HPGD-/-) mice due to requirement for embryo 15-HPGD activity. |
ongoing research
therapeutic application
unassigned |
1
1
0 |
| 1.1.1.141 | Acromegaly |
34485865 |
Treatment of acromegaly by rosiglitazone via upregulating 15-PGDH in both pituitary adenoma and liver. |
causal interaction
therapeutic application
unassigned |
3
3
0 |
| 1.1.1.141 | Acute Kidney Injury |
32231583 |
Pharmacologic Blockade of 15-PGDH Protects Against Acute Renal Injury Induced by LPS in Mice. |
ongoing research
therapeutic application
unassigned |
4
2
0 |
| 1.1.1.141 | Acute Kidney Injury |
33459127 |
15-Hydroxyprostaglandin dehydrogenase inhibitor prevents contrast-induced acute kidney injury. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
2
4
0 |
| 1.1.1.141 | Adenocarcinoma |
19584167 |
15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
2 |
| 1.1.1.141 | Adenocarcinoma |
19917058 |
Reduction of 15-hydroxyprostaglandin dehydrogenase expression is an independent predictor of poor survival associated with enhanced cell proliferation in gastric adenocarcinoma. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
3
2 |
| 1.1.1.141 | Adenocarcinoma |
21916491 |
11-Oxoeicosatetraenoic acid is a cyclooxygenase-2/15-hydroxyprostaglandin dehydrogenase-derived antiproliferative eicosanoid. |
diagnostic usage
ongoing research
unassigned |
1
2
0 |
| 1.1.1.141 | Adenocarcinoma |
24949321 |
Relationship between 15-hydroxyprostaglandin dehydrogenase and gastric adenocarcinoma. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
2
4
0 |
