EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category  |
Confidence Level |
|---|
   3.4.24.84 | Colorectal Neoplasms |
27729169 |
Mutational and expressional alterations of ZMPSTE24, DNA damage response-related gene, in gastric and colorectal cancers. |
causal interaction
diagnostic usage
ongoing research
unassigned |
2
3
4
0 |
| 3.4.24.84 | Laminopathies |
16297189 |
Homozygous and compound heterozygous mutations in ZMPSTE24 cause the laminopathy restrictive dermopathy. |
causal interaction
unassigned |
3
0 |
| 3.4.24.84 | Laminopathies |
16364671 |
Laminopathies: multisystem dystrophy syndromes. |
causal interaction
unassigned |
3
0 |
| 3.4.24.84 | Laminopathies |
19645629 |
LMNA, ZMPSTE24, and LBR are not mutated in scleroderma. |
causal interaction
unassigned |
1
0 |
| 3.4.24.84 | Laminopathies |
20074077 |
HIV protease inhibitors inhibit FACE1/ZMPSTE24: a mechanism for acquired lipodystrophy in patients on highly active antiretroviral therapy? |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 3.4.24.84 | Laminopathies |
27120622 |
A Heterozygous ZMPSTE24 Mutation Associated with Severe Metabolic Syndrome, Ectopic Fat Accumulation, and Dilated Cardiomyopathy. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
1
1
0 |
| 3.4.24.84 | Laminopathies |
33590450 |
Lonafarnib: First Approval. |
causal interaction
therapeutic application
unassigned |
2
4
0 |
| 3.4.24.84 | Lipodystrophy |
26602028 |
A novel homozygous LMNA mutation (p.Met540Ile) causes mandibuloacral dysplasia type A. |
causal interaction
unassigned |
3
0 |
| 3.4.24.84 | Progeria |
19851476 |
Genomic Instability and DNA Damage Responses in Progeria Arising from Defective Maturation of Prelamin A. |
causal interaction
unassigned |
4
0 |
| 3.4.24.84 | Progeria |
20458013 |
Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging. |
causal interaction
unassigned |
4
0 |
