EC Number   |
Disease |
PubMed ID  |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.21.B12 | Endometrial Neoplasms |
11344246 |
Kallikrein 4 (KLK4), a new member of the human kallikrein gene family is up-regulated by estrogen and progesterone in the human endometrial cancer cell line, KLE. |
ongoing research
unassigned |
3
0 |
| 3.4.21.B12 | Carcinoma |
11489814 |
Human kallikrein 4 (KLK4) is highly expressed in serous ovarian carcinomas. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
2
0 |
| 3.4.21.B12 | Prostatic Neoplasms |
12142379 |
Detection of human kallikrein 4 in healthy and cancerous prostatic tissues by immunofluorometry and immunohistochemistry. |
diagnostic usage
ongoing research
unassigned |
1
2
0 |
| 3.4.21.B12 | Prostatic Neoplasms |
15059887 |
Kallikrein 4 is a predominantly nuclear protein and is overexpressed in prostate cancer. |
causal interaction
diagnostic usage
unassigned |
3
4
0 |
| 3.4.21.B12 | Amelogenesis Imperfecta |
15235027 |
Mutation in kallikrein 4 causes autosomal recessive hypomaturation amelogenesis imperfecta. |
causal interaction
unassigned |
2
0 |
| 3.4.21.B12 | Ovarian Neoplasms |
15262123 |
Kallikrein 4 is associated with paclitaxel resistance in ovarian cancer. |
causal interaction
diagnostic usage
unassigned |
4
1
0 |
| 3.4.21.B12 | Carcinoma |
15716231 |
Kallikrein 4 expression is up-regulated in epithelial ovarian carcinoma cells in effusions. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
4
0 |
| 3.4.21.B12 | Carcinoma, Ovarian Epithelial |
15716231 |
Kallikrein 4 expression is up-regulated in epithelial ovarian carcinoma cells in effusions. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
4
0 |
| 3.4.21.B12 | Prostatic Neoplasms |
16172196 |
Kallikrein 4 (hK4) and prostate-specific antigen (PSA) are associated with the loss of E-cadherin and an epithelial-mesenchymal transition (EMT)-like effect in prostate cancer cells. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
3
1
0 |
| 3.4.21.B12 | Prostatic Neoplasms |
16322328 |
Compartmentalized expression of kallikrein 4 (KLK4/hK4) isoforms in prostate cancer: nuclear, cytoplasmic and secreted forms. |
causal interaction
diagnostic usage
unassigned |
3
4
0 |
