EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
   3.4.21.92 | Parasitic Diseases |
32471865 |
A chemical inhibitor of heat shock protein 78 (HSP78) from Leishmania donovani represents a potential antileishmanial drug candidate. |
ongoing research
therapeutic application
unassigned |
1
3
0 |
| 3.4.21.92 | Tuberculosis |
20975890 |
A ClpP protein model as tuberculosis target for screening marine compounds. |
unassigned |
0 |
| 3.4.21.92 | Malaria |
20545854 |
A cyanobacterial serine protease of Plasmodium falciparum is targeted to the apicoplast and plays an important role in its growth and development. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 3.4.21.92 | Malaria |
28917450 |
A novel class of Plasmodial ClpP protease inhibitors as potential antimalarial agents. |
causal interaction
therapeutic application
unassigned |
2
3
0 |
| 3.4.21.92 | Dehydration |
9375397 |
A nuclear gene, erd1, encoding a chloroplast-targeted Clp protease regulatory subunit homolog is not only induced by water stress but also developmentally up-regulated during senescence in Arabidopsis thaliana. |
therapeutic application
unassigned |
1
0 |
| 3.4.21.92 | Tuberculosis |
26919556 |
Acyldepsipeptide antibiotics kill mycobacteria by preventing the physiological functions of the ClpP1P2 protease. |
ongoing research
unassigned |
1
0 |
| 3.4.21.92 | Infections |
32323346 |
Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus. |
ongoing research
therapeutic application
unassigned |
1
2
0 |
| 3.4.21.92 | Tuberculosis |
32123115 |
An allosteric switch regulates Mycobacterium tuberculosis ClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR. |
therapeutic application
unassigned |
1
0 |
| 3.4.21.92 | Plant Diseases |
33326777 |
Antagonistic Regulation by CPN60A and CLPC1 of TRXL1 that Regulates MDH Activity Leading to Plant Disease Resistance and Thermotolerance. |
ongoing research
therapeutic application
unassigned |
1
1
0 |
| 3.4.21.92 | Tuberculosis |
26586403 |
Anti-tuberculosis lead molecules from natural products targeting Mycobacterium tuberculosis ClpC1. |
unassigned |
0 |
