EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level  |
|---|
   3.4.21.92 | Anemia, Hypochromic |
15549267 |
Chlorosis during nitrogen starvation is altered by carbon dioxide and temperature status and is mediated by the ClpP1 protease in Synechococcus elongatus. |
unassigned |
0 |
| 3.4.21.92 | Anemia, Hypochromic |
15563614 |
Inactivation of the clpC1 gene encoding a chloroplast Hsp100 molecular chaperone causes growth retardation, leaf chlorosis, lower photosynthetic activity, and a specific reduction in photosystem content. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 3.4.21.92 | Anemia, Hypochromic |
20382967 |
ClpC1, an ATP-dependent Clp protease in plastids, is involved in iron homeostasis in Arabidopsis leaves. |
unassigned |
0 |
| 3.4.21.92 | Blindness |
32873765 |
The ClpX and ClpP2 Orthologs of Chlamydia trachomatis Perform Discrete and Essential Functions in Organism Growth and Development. |
unassigned |
0 |
| 3.4.21.92 | Dehydration |
9375397 |
A nuclear gene, erd1, encoding a chloroplast-targeted Clp protease regulatory subunit homolog is not only induced by water stress but also developmentally up-regulated during senescence in Arabidopsis thaliana. |
therapeutic application
unassigned |
1
0 |
| 3.4.21.92 | Hypersensitivity |
9299335 |
Communication of ClpXP protease hypersensitivity to bacteriophage Mu repressor isoforms. |
causal interaction
unassigned |
1
0 |
| 3.4.21.92 | Infections |
9570408 |
The ClpC ATPase of Listeria monocytogenes is a general stress protein required for virulence and promoting early bacterial escape from the phagosome of macrophages. |
ongoing research
unassigned |
4
0 |
| 3.4.21.92 | Infections |
17185548 |
Proteomic comparison of Mycobacterium avium subspecies paratuberculosis grown in vitro and isolated from clinical cases of ovine paratuberculosis. |
unassigned |
0 |
| 3.4.21.92 | Infections |
22359499 |
Mycobacterium tuberculosis ClpP1 and ClpP2 Function Together in Protein Degradation and Are Required for Viability in vitro and During Infection. |
ongoing research
therapeutic application
unassigned |
4
1
0 |
| 3.4.21.92 | Infections |
27831584 |
The development of small-molecule modulators for ClpP protease activity. |
causal interaction
unassigned |
4
0 |
