EC Number   |
Disease |
PubMed ID  |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.17.23 | Down Syndrome |
9325052 |
Cloning of the TMPRSS2 gene, which encodes a novel serine protease with transmembrane, LDLRA, and SRCR domains and maps to 21q22.3. |
unassigned |
0 |
| 3.4.17.23 | Carcinogenesis |
10485450 |
Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
2
4
0 |
| 3.4.17.23 | Prostatic Neoplasms |
10485450 |
Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
2
4
0 |
| 3.4.17.23 | Neoplasm Metastasis |
11245484 |
Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
2
3 |
| 3.4.17.23 | Neoplasms |
11245484 |
Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
2
3 |
| 3.4.17.23 | Prostatic Neoplasms |
11245484 |
Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
2
3 |
| 3.4.17.23 | Carcinoma |
11414763 |
Mutation analyses of 268 candidate genes in human tumor cell lines. |
diagnostic usage
ongoing research
unassigned |
1
4
0 |
| 3.4.17.23 | Neoplasms |
11414763 |
Mutation analyses of 268 candidate genes in human tumor cell lines. |
diagnostic usage
ongoing research
unassigned |
1
4
0 |
| 3.4.17.23 | Adenocarcinoma |
11745466 |
The TMPRSS2 gene encoding transmembrane serine protease is overexpressed in a majority of prostate cancer patients: detection of mutated TMPRSS2 form in a case of aggressive disease. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
2 |
| 3.4.17.23 | Neoplasms |
11745466 |
The TMPRSS2 gene encoding transmembrane serine protease is overexpressed in a majority of prostate cancer patients: detection of mutated TMPRSS2 form in a case of aggressive disease. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
2 |
