EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
   3.3.2.6 | Nephrotic Syndrome |
14986086 |
5-Lipoxygenase and leukotriene A4 hydrolase expression in primary nephrotic syndrome. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
3
3
1
0 |
| 3.3.2.6 | Glioma |
19919819 |
5-lipoxygenase pathway promotes cell proliferation in human glioma cell lines. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
4
2
0 |
| 3.3.2.6 | Tuberculosis, Meningeal |
33416499 |
A Bayesian analysis of the association between Leukotriene A4 Hydrolase genotype and survival in tuberculous meningitis. |
diagnostic usage
unassigned |
3
0 |
| 3.3.2.6 | Myocardial Infarction |
16282974 |
A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
3
3
2
0 |
| 3.3.2.6 | Chemical and Drug Induced Liver Injury |
30363837 |
Adjunctive dexamethasone for the treatment of HIV-uninfected adults with tuberculous meningitis stratified by Leukotriene A4 hydrolase genotype (LAST ACT): Study protocol for a randomised double blind placebo controlled non-inferiority trial. |
causal interaction
therapeutic application
unassigned |
1
4
0 |
| 3.3.2.6 | Tuberculosis, Meningeal |
30363837 |
Adjunctive dexamethasone for the treatment of HIV-uninfected adults with tuberculous meningitis stratified by Leukotriene A4 hydrolase genotype (LAST ACT): Study protocol for a randomised double blind placebo controlled non-inferiority trial. |
causal interaction
therapeutic application
unassigned |
1
4
0 |
| 3.3.2.6 | Asthma |
20810156 |
ALOX5AP and LTA4H polymorphisms modify augmentation of bronchodilator responsiveness by leukotriene modifiers in Latinos. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
1
3
1
0 |
| 3.3.2.6 | Tuberculosis |
23874453 |
An enzyme that inactivates the inflammatory mediator leukotriene b4 restricts mycobacterial infection. |
unassigned |
0 |
| 3.3.2.6 | Asthma |
30135247 |
An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 3.3.2.6 | Infections |
21112816 |
Association analysis of the LTA4H gene polymorphisms and pulmonary tuberculosis in 9115 subjects. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
1
4
2 |
