EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category  |
Confidence Level |
|---|
   3.1.1.106 | Neoplasms |
25422431 |
MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
2
1 |
| 3.1.1.106 | Neoplasms |
29410655 |
MacroD1 Is a Promiscuous ADP-Ribosyl Hydrolase Localized to Mitochondria. |
causal interaction
unassigned |
3
0 |
| 3.1.1.106 | Neoplasms |
29880585 |
MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
1 |
| 3.1.1.106 | Neoplasms |
30076143 |
MACROD2, an Original Cause of CIN? |
causal interaction
unassigned |
4
0 |
| 3.1.1.106 | Neoplasms |
30619475 |
Mono-ADP-Ribosylhydrolase MACROD2 Is Dispensable for Murine Responses to Metabolic and Genotoxic Insults. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
2
1
0 |
| 3.1.1.106 | Neoplasms |
31921812 |
Copy Number Variation Pattern for Discriminating MACROD2 States of Colorectal Cancer Subtypes. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
2
3
1
0 |
| 3.1.1.106 | Colorectal Neoplasms |
30237848 |
MACROD2 deletions cause impaired PARP1 activity and chromosome instability in colorectal cancer. |
causal interaction
diagnostic usage
unassigned |
1
1
0 |
| 3.1.1.106 | Intellectual Disability |
31055587 |
Intragenic Deletion in MACROD2: A Family with Complex Phenotypes Including Microcephaly, Intellectual Disability, Polydactyly, Renal and Pancreatic Malformations. |
diagnostic usage
unassigned |
3
0 |
| 3.1.1.106 | Polycystic Ovary Syndrome |
30343302 |
High Genetic Risk Scores of ASIC2, MACROD2, CHRM3, and C2orf83 Genetic Variants Associated with Polycystic Ovary Syndrome Impair Insulin Sensitivity and Interact with Energy Intake in Korean Women. |
diagnostic usage
unassigned |
3
0 |
| 3.1.1.106 | Breast Neoplasms |
25422431 |
MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
2
1 |
