EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category  |
Confidence Level |
|---|
    2.6.1.16 | choline o-acetyltransferase deficiency |
29395675 |
Congenital myasthenic syndromes in Turkey: Clinical clues and prognosis with long term follow-up. |
causal interaction
unassigned |
4
0 |
| 2.6.1.16 | Glucose Intolerance |
11118009 |
Overexpression of glutamine: fructose-6-phosphate amidotransferase in the liver of transgenic mice results in enhanced glycogen storage, hyperlipidemia, obesity, and impaired glucose tolerance. |
causal interaction
ongoing research
unassigned |
3
1
0 |
| 2.6.1.16 | Insulin Resistance |
1460020 |
Molecular cloning, cDNA sequence, and bacterial expression of human glutamine:fructose-6-phosphate amidotransferase. |
causal interaction
unassigned |
4
0 |
| 2.6.1.16 | Insulin Resistance |
1743436 |
New insights into the metabolic regulation of insulin action and insulin resistance: role of glucose and amino acids. |
causal interaction
unassigned |
1
0 |
| 2.6.1.16 | Insulin Resistance |
10067838 |
Mechanism of hexosamine-induced insulin resistance in transgenic mice overexpressing glutamine:fructose-6-phosphate amidotransferase: decreased glucose transporter GLUT4 translocation and reversal by treatment with thiazolidinedione. |
causal interaction
therapeutic application
unassigned |
1
3
0 |
| 2.6.1.16 | Insulin Resistance |
11167021 |
Cloning and characterization of mouse glutamine:fructose-6-phosphate amidotransferase 2 gene promoter. |
causal interaction
unassigned |
1
0 |
| 2.6.1.16 | Insulin Resistance |
16555472 |
Effect of sucrose and saturated-fat diets on mRNA levels of genes limiting muscle fatty acid and glucose supply in rats. |
causal interaction
unassigned |
2
0 |
| 2.6.1.16 | Insulin Resistance |
17574229 |
Glutamine fructose-6-phosphate amidotransferase (GFAT) gene expression and activity in patients with type 2 diabetes: inter-relationships with hyperglycaemia and oxidative stress. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
3
1
0 |
| 2.6.1.16 | Insulin Resistance |
19036880 |
Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin. |
diagnostic usage
ongoing research
unassigned |
1
1
0 |
| 2.6.1.16 | Neoplasms |
28186970 |
High expression of GFAT1 predicts unfavorable prognosis in patients with hepatocellular carcinoma. |
causal interaction
diagnostic usage
unassigned |
4
4
0 |
