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EC Number
Disease
PubMed ID
Title of Publication
Category
Confidence Level
Adenocarcinoma
Absence of tRNA-guanine transglycosylase in a human colon adenocarcinoma cell line.
ongoing research
4
Adenocarcinoma
Absence of tRNA-guanine transglycosylase in a human colon adenocarcinoma cell line.
unassigned
0
Colonic Neoplasms
Elevated expression level of 60-kDa subunit of tRNA-guanine transglycosylase in colon cancer.
diagnostic usage
4
Colonic Neoplasms
Elevated expression level of 60-kDa subunit of tRNA-guanine transglycosylase in colon cancer.
unassigned
0
Dysentery, Bacillary
Structure-based drug design: exploring the proper filling of apolar pockets at enzyme active sites.
causal interaction
1
Dysentery, Bacillary
Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT.
causal interaction
1
Dysentery, Bacillary
An Immucillin-based Transition State-Analogous Inhibitor of tRNA-Guanine Transglycosylase (TGT).
causal interaction
1
Dysentery, Bacillary
High-Affinity Inhibitors of tRNA-Guanine Transglycosylase Replacing the Function of a Structural Water Cluster.
diagnostic usage
1
Dysentery, Bacillary
Replacement of water molecules in a phosphate binding site by furanoside-appended lin-benzoguanine ligands of tRNA-guanine transglycosylase (TGT).
diagnostic usage
1
Dysentery, Bacillary
A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase.
therapeutic application
4
Results 1 - 10 of 42 > >>