EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
   2.4.1.223 | Adenocarcinoma |
11382776 |
A novel endo-beta-galactosidase from Clostridium perfringens that liberates the disaccharide GlcNAcalpha 1-->Gal from glycans specifically expressed in the gastric gland mucous cell-type mucin. |
ongoing research
unassigned |
1
0 |
| 2.4.1.223 | Carcinogenesis |
32347583 |
Aberrant glycosaminoglycan biosynthesis by tumor suppressor EXTL2 deficiency promotes liver inflammation and tumorigenesis through Toll-like 4 receptor signaling. |
causal interaction
ongoing research
unassigned |
4
1
0 |
| 2.4.1.223 | glucuronosyl-galactosyl-proteoglycan 4-alpha-n-acetylglucosaminyltransferase deficiency |
32347583 |
Aberrant glycosaminoglycan biosynthesis by tumor suppressor EXTL2 deficiency promotes liver inflammation and tumorigenesis through Toll-like 4 receptor signaling. |
causal interaction
ongoing research
unassigned |
4
1
0 |
| 2.4.1.223 | Neoplasms |
32347583 |
Aberrant glycosaminoglycan biosynthesis by tumor suppressor EXTL2 deficiency promotes liver inflammation and tumorigenesis through Toll-like 4 receptor signaling. |
causal interaction
ongoing research
unassigned |
4
1
0 |
| 2.4.1.223 | Kashin-Beck Disease |
32517548 |
Altered Expression of Aggrecan, FAM20B, B3GALT6, and EXTL2 in Patients with Osteoarthritis and Kashin-Beck Disease. |
causal interaction
diagnostic usage
unassigned |
2
1
0 |
| 2.4.1.223 | Osteoarthritis |
32517548 |
Altered Expression of Aggrecan, FAM20B, B3GALT6, and EXTL2 in Patients with Osteoarthritis and Kashin-Beck Disease. |
causal interaction
diagnostic usage
unassigned |
2
1
0 |
| 2.4.1.223 | Pancreatic Neoplasms |
16441422 |
Clinical utility of quantitative RT-PCR targeted to alpha1,4-N-acetylglucosaminyltransferase mRNA for detection of pancreatic cancer. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
4
3
0 |
| 2.4.1.223 | Exostoses, Multiple Hereditary |
17237233 |
Expression of rib-1, a Caenorhabditis elegans homolog of the human tumor suppressor EXT genes, is indispensable for heparan sulfate synthesis and embryonic morphogenesis. |
causal interaction
ongoing research
unassigned |
1
1
0 |
| 2.4.1.223 | Neoplasms |
17237233 |
Expression of rib-1, a Caenorhabditis elegans homolog of the human tumor suppressor EXT genes, is indispensable for heparan sulfate synthesis and embryonic morphogenesis. |
causal interaction
ongoing research
unassigned |
1
1
0 |
| 2.4.1.223 | Neoplasms |
23395820 |
EXTL2, a Member of the EXT Family of Tumor Suppressors, Controls Glycosaminoglycan Biosynthesis in a Xylose Kinase-dependent Manner. |
unassigned |
0 |
