EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
2.3.1.12 | Alzheimer Disease |
4004169 |
An immunochemical study of the pyruvate dehydrogenase deficit in Alzheimer's disease brain. |
causal interaction diagnostic usage ongoing research unassigned |
1 2 2 0 |
2.3.1.12 | Autoimmune Diseases |
3049806 |
Autoantibodies of primary biliary cirrhosis recognize dihydrolipoamide acetyltransferase and inhibit enzyme function. |
diagnostic usage ongoing research unassigned |
3 4 0 |
2.3.1.12 | Bile Duct Neoplasms |
12108679 |
Molecular cloning, and characterization and expression of dihydrolipoamide acetyltransferase component of murine pyruvate dehydrogenase complex in bile duct cancer cells. |
causal interaction ongoing research unassigned |
3 4 0 |
2.3.1.12 | Hepatitis |
7519986 |
Identification of the dihydrolipoamide acetyltransferase subunit of the human pyruvate dehydrogenase complex as an autoantigen in halothane hepatitis. Molecular mimicry of trifluoroacetyl-lysine by lipoic acid. |
causal interaction diagnostic usage ongoing research unassigned |
3 1 2 0 |
2.3.1.12 | Liver Cirrhosis, Biliary |
1370237 |
Membrane dihydrolipoamide acetyltransferase (E2) on human biliary epithelial cells in primary biliary cirrhosis. |
causal interaction diagnostic usage ongoing research unassigned |
1 3 4 0 |
2.3.1.12 | Liver Cirrhosis, Biliary |
1714873 |
Distribution of dihydrolipoamide acetyltransferase (E2) in the liver and portal lymph nodes of patients with primary biliary cirrhosis: an immunohistochemical study. |
causal interaction diagnostic usage ongoing research unassigned |
1 4 4 0 |
2.3.1.12 | Liver Cirrhosis, Biliary |
1729364 |
A lipoyl synthetic octadecapeptide of dihydrolipoamide acetyltransferase specifically recognized by anti-M2 autoantibodies in primary biliary cirrhosis. |
causal interaction diagnostic usage unassigned |
1 3 0 |
2.3.1.12 | Liver Cirrhosis, Biliary |
2187198 |
Reactivity of primary biliary cirrhosis sera with Escherichia coli dihydrolipoamide acetyltransferase (E2p): characterization of the main immunogenic region. |
unassigned |
0 |
2.3.1.12 | Liver Cirrhosis, Biliary |
2455013 |
The autoepitope of the 74-kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase. |
unassigned |
0 |
2.3.1.12 | Liver Cirrhosis, Biliary |
2473022 |
Antimitochondrial autoantibodies in primary biliary cirrhosis recognize cross-reactive epitope(s) on protein X and dihydrolipoamide acetyltransferase of pyruvate dehydrogenase complex. |
causal interaction ongoing research therapeutic application unassigned |
4 1 1 0 |