EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
    1.5.5.2 | Neoplasms |
30545412 |
1-Pyrroline-5-carboxylate released by prostate Cancer cell inhibit T cell proliferation and function by targeting SHP1/cytochrome c oxidoreductase/ROS Axis. |
causal interaction
unassigned |
4
0 |
| 1.5.5.2 | Dehydration |
8776899 |
A nuclear gene encoding mitochondrial proline dehydrogenase, an enzyme involved in proline metabolism, is upregulated by proline but downregulated by dehydration in Arabidopsis. |
unassigned |
0 |
| 1.5.5.2 | Dehydration |
12376638 |
ACTCAT, a novel cis-acting element for proline- and hypoosmolarity-responsive expression of the ProDH gene encoding proline dehydrogenase in Arabidopsis. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 1.5.5.2 | Hypersensitivity |
11788754 |
Altered levels of proline dehydrogenase cause hypersensitivity to proline and its analogs in Arabidopsis. |
diagnostic usage
unassigned |
1
0 |
| 1.5.5.2 | DiGeorge Syndrome |
24853458 |
Association of COMT and PRODH gene variants with intelligence quotient (IQ) and executive functions in 22q11.2DS subjects. |
unassigned |
0 |
| 1.5.5.2 | Carcinogenesis |
31911619 |
Cancer progression is mediated by proline catabolism in non-small cell lung cancer. |
causal interaction
unassigned |
4
0 |
| 1.5.5.2 | Neoplasms |
31911619 |
Cancer progression is mediated by proline catabolism in non-small cell lung cancer. |
causal interaction
unassigned |
4
0 |
| 1.5.5.2 | Neoplasms |
33818628 |
Collagen metabolism as a regulator of proline dehydrogenase/proline oxidase-dependent apoptosis/autophagy. |
causal interaction
therapeutic application
unassigned |
3
3
0 |
| 1.5.5.2 | Neoplasms |
32159324 |
Covalent Modification of the Flavin in Proline Dehydrogenase by Thiazolidine-2-Carboxylate. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
1
4
0 |
| 1.5.5.2 | Infections |
27526663 |
Differential control and function of Arabidopsis ProDH1 and ProDH2 genes upon infection with biotrophic and necrotrophic pathogens. |
ongoing research
unassigned |
1
0 |
