EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category  |
Confidence Level |
|---|
   1.14.99.38 | Colitis |
31220227 |
The Oxysterol Synthesising Enzyme CH25H Contributes to the Development of Intestinal Fibrosis. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
4
1
0 |
| 1.14.99.38 | Colitis |
32859970 |
Cholesterol 25-hydroxylase protects against experimental colitis in mice by modulating epithelial gut barrier function. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
4
4
0 |
| 1.14.99.38 | Infections |
21263022 |
Listeria monocytogenes Infection Induces Prosurvival Metabolic Signaling in Macrophages. |
causal interaction
unassigned |
3
0 |
| 1.14.99.38 | Infections |
21570957 |
Selective role for tumor necrosis factor-?, but not interleukin-1 or Kupffer cells, in down-regulation of CYP3A11 and CYP3A25 in livers of mice infected with a noninvasive intestinal pathogen. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
1
3
4
2 |
| 1.14.99.38 | Infections |
24994901 |
25-Hydroxycholesterol acts as an amplifier of inflammatory signaling. |
causal interaction
unassigned |
1
0 |
| 1.14.99.38 | Infections |
25467815 |
Interferon-inducible cholesterol-25-hydroxylase inhibits hepatitis C virus replication via distinct mechanisms. |
causal interaction
therapeutic application
unassigned |
3
2
0 |
| 1.14.99.38 | Infections |
25903345 |
Identification of Cholesterol 25-Hydroxylase as a Novel Host Restriction Factor and a Part of the Primary Innate Immune Responses against Hepatitis C Virus Infection. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
3
3
0 |
| 1.14.99.38 | Infections |
28631596 |
Cholesterol 25-hydroxylase acts as a host restriction factor on pseudorabies virus replication. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
3
2
1 |
| 1.14.99.38 | Infections |
31151272 |
Cholesterol-25-hydroxylase Is a Chicken ISG That Restricts ALV-J Infection by Producing 25-hydroxycholesterol. |
causal interaction
therapeutic application
unassigned |
2
1
0 |
| 1.14.99.38 | Influenza, Human |
24994901 |
25-Hydroxycholesterol acts as an amplifier of inflammatory signaling. |
causal interaction
unassigned |
1
0 |
