EC Number   |
Disease  |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.5.3.18 | Asthma |
24465497 |
Overexpression of dimethylarginine dimethylaminohydrolase 1 attenuates airway inflammation in a mouse model of asthma. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
1
4
1 |
| 3.5.3.18 | Atherosclerosis |
17293168 |
Taurine protects against low-density lipoprotein-induced endothelial dysfunction by the DDAH/ADMA pathway. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 3.5.3.18 | Atherosclerosis |
19603041 |
Dimethylarginine dimethylaminohydrolase in rat penile tissue: reduced enzyme activity is responsible for erectile dysfunction in a rat model of atherosclerosis. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
2
1
0 |
| 3.5.3.18 | Atherosclerosis |
20348244 |
Dimethylarginine dimethylaminohydrolase overexpression ameliorates atherosclerosis in apolipoprotein E-deficient mice by lowering asymmetric dimethylarginine. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 3.5.3.18 | Atherosclerosis |
20462645 |
Improvement of endothelial dysfunction in atherosclerotic rabbit aortas by ex vivo gene transferring of dimethylarginine dimethylaminohydrolase-2. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
1
3
3 |
| 3.5.3.18 | Atherosclerosis |
24690995 |
Effect of Lowering Asymmetric Dimethylarginine (ADMA) on Vascular Pathology in Atherosclerotic ApoE-Deficient Mice with Reduced Renal Mass. |
diagnostic usage
ongoing research
unassigned |
1
4
0 |
| 3.5.3.18 | Atherosclerosis |
26226438 |
FoxO1 regulates asymmetric dimethylarginine via downregulation of dimethylaminohydrolase 1 in human endothelial cells and subjects with atherosclerosis. |
ongoing research
unassigned |
4
0 |
| 3.5.3.18 | Atherosclerosis |
33535073 |
Treatment of atherosclerosis through transplantation of endothelial progenitor cells overexpressing dimethylarginine dimethylaminohydrolase (DDAH) in rabbits. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
2
4
0 |
| 3.5.3.18 | Atherosclerosis |
34438260 |
Hyperuricemia induces endothelial dysfunction and accelerates atherosclerosis by disturbing the asymmetric dimethylarginine/dimethylarginine dimethylaminotransferase 2 pathway. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
| 3.5.3.18 | Brain Ischemia |
33271854 |
Sequence Variation in the DDAH1 Gene Predisposes for Delayed Cerebral Ischemia in Subarachnoidal Hemorrhage. |
causal interaction
ongoing research
unassigned |
1
1
0 |
