EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level  |
|---|
   3.5.3.18 | Breast Neoplasms |
33442289 |
Circ_0004771 Accelerates Cell Carcinogenic Phenotypes via Suppressing miR-1253-Mediated DDAH1 Inhibition in Breast Cancer. |
unassigned |
0 |
| 3.5.3.18 | Bronchopulmonary Dysplasia |
26663142 |
A single nucleotide polymorphism in the dimethylarginine dimethylaminohydrolase gene is associated with lower risk of pulmonary hypertension in bronchopulmonary dysplasia. |
causal interaction
diagnostic usage
unassigned |
4
3
0 |
| 3.5.3.18 | Bronchopulmonary Dysplasia |
34151866 |
DDAH1 SNP rs480414 that protects against the development of pulmonary hypertension in bronchopulmonary dysplasia results in lower nitric oxide production in neonatal cord blood-derived lymphoblastoid cell lines. |
causal interaction
therapeutic application
unassigned |
2
1
0 |
| 3.5.3.18 | Carcinogenesis |
33442289 |
Circ_0004771 Accelerates Cell Carcinogenic Phenotypes via Suppressing miR-1253-Mediated DDAH1 Inhibition in Breast Cancer. |
unassigned |
0 |
| 3.5.3.18 | Carcinoma |
24155659 |
DNA methylation profiling revealed promoter hypermethylation-induced silencing of p16, DDAH2 and DUSP1 in primary oral squamous cell carcinoma. |
diagnostic usage
unassigned |
1
0 |
| 3.5.3.18 | Carcinoma, Hepatocellular |
28741166 |
A new key player in VEGF-dependent angiogenesis in human hepatocellular carcinoma: dimethylarginine dimethylaminohydrolase 1. |
causal interaction
unassigned |
3
0 |
| 3.5.3.18 | Cardiomegaly |
28819685 |
Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction. |
causal interaction
therapeutic application
unassigned |
1
2
0 |
| 3.5.3.18 | Cardiomegaly |
32762558 |
Enhanced dimethylarginine degradation improves coronary flow reserve and exercise tolerance in Duchenne muscular dystrophy carrier mice. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
1
2
0 |
| 3.5.3.18 | Cardiovascular Abnormalities |
16959216 |
Involvement of DDAH/ADMA/NOS pathway in nicotine-induced endothelial dysfunction. |
causal interaction
unassigned |
3
0 |
| 3.5.3.18 | Cardiovascular Diseases |
19331593 |
Dimethylarginine dimethylaminohydrolase regulation: a novel therapeutic target in cardiovascular disease. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
