EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.5.3.18 | Brain Ischemia |
33433489 |
DDAH2 (-449 G/C) G allele is positively associated with leukoaraiosis in northeastern China: a double-blind, intergroup comparison, case-control study. |
causal interaction unassigned |
3 0 |
3.5.3.18 | Breast Neoplasms |
29070803 |
MiR-193b regulates breast cancer cell migration and vasculogenic mimicry by targeting dimethylarginine dimethylaminohydrolase 1. |
ongoing research therapeutic application unassigned |
4 1 0 |
3.5.3.18 | Breast Neoplasms |
30611984 |
Small molecule inhibition of DDAH1 significantly attenuates triple negative breast cancer cell vasculogenic mimicry in vitro. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 2 1 4 |
3.5.3.18 | Breast Neoplasms |
33442289 |
Circ_0004771 Accelerates Cell Carcinogenic Phenotypes via Suppressing miR-1253-Mediated DDAH1 Inhibition in Breast Cancer. |
unassigned |
0 |
3.5.3.18 | Bronchopulmonary Dysplasia |
26663142 |
A single nucleotide polymorphism in the dimethylarginine dimethylaminohydrolase gene is associated with lower risk of pulmonary hypertension in bronchopulmonary dysplasia. |
causal interaction diagnostic usage unassigned |
4 3 0 |
3.5.3.18 | Bronchopulmonary Dysplasia |
34151866 |
DDAH1 SNP rs480414 that protects against the development of pulmonary hypertension in bronchopulmonary dysplasia results in lower nitric oxide production in neonatal cord blood-derived lymphoblastoid cell lines. |
causal interaction therapeutic application unassigned |
2 1 0 |
3.5.3.18 | Carcinogenesis |
33442289 |
Circ_0004771 Accelerates Cell Carcinogenic Phenotypes via Suppressing miR-1253-Mediated DDAH1 Inhibition in Breast Cancer. |
unassigned |
0 |
3.5.3.18 | Carcinoma |
24155659 |
DNA methylation profiling revealed promoter hypermethylation-induced silencing of p16, DDAH2 and DUSP1 in primary oral squamous cell carcinoma. |
diagnostic usage unassigned |
1 0 |
3.5.3.18 | Carcinoma, Hepatocellular |
28741166 |
A new key player in VEGF-dependent angiogenesis in human hepatocellular carcinoma: dimethylarginine dimethylaminohydrolase 1. |
causal interaction unassigned |
3 0 |
3.5.3.18 | Cardiomegaly |
28819685 |
Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction. |
causal interaction therapeutic application unassigned |
1 2 0 |