EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.21.B12 | Carcinoma |
11489814 |
Human kallikrein 4 (KLK4) is highly expressed in serous ovarian carcinomas. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
2
0 |
| 3.4.21.B12 | Carcinoma |
15716231 |
Kallikrein 4 expression is up-regulated in epithelial ovarian carcinoma cells in effusions. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
4
0 |
| 3.4.21.B12 | Carcinoma |
24854539 |
Low mRNA expression levels of kallikrein-related peptidase 4 (KLK4) predict short-term relapse in patients with laryngeal squamous cell carcinoma. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
3
1 |
| 3.4.21.B12 | Carcinoma |
28743213 |
Kallikrein-related peptidase 4 contributes to the tumor metastasis of oral squamous cell carcinoma. |
causal interaction
unassigned |
4
0 |
| 3.4.21.B12 | Carcinoma, Ovarian Epithelial |
15716231 |
Kallikrein 4 expression is up-regulated in epithelial ovarian carcinoma cells in effusions. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
4
0 |
| 3.4.21.B12 | Carcinoma, Squamous Cell |
33841682 |
Elevated levels of both microRNA 378 (miR-378) and kallikrein-related peptidase 4 (KLK4) mRNA are associated with an unfavorable prognosis in triple-negative breast cancer. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
4
3
0 |
| 3.4.21.B12 | Colonic Neoplasms |
20056842 |
Kallikrein-related peptidase 4: a new activator of the aberrantly expressed protease-activated receptor 1 in colon cancer cells. |
ongoing research
unassigned |
4
0 |
| 3.4.21.B12 | Endometrial Neoplasms |
11344246 |
Kallikrein 4 (KLK4), a new member of the human kallikrein gene family is up-regulated by estrogen and progesterone in the human endometrial cancer cell line, KLE. |
ongoing research
unassigned |
3
0 |
| 3.4.21.B12 | Endometrial Neoplasms |
20009893 |
Kallikrein 4 overexpression in endometrial carcinoma and upregulation by estrogen via mitogen-activated protein kinase signal pathway. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
3
3
1 |
| 3.4.21.B12 | Endometriosis |
32400148 |
Kallikrein-related peptidase 4 promotes migration and invasion of endometrial stromal cells in endometriosis by inducing epithelial-mesenchymal transition. |
causal interaction
ongoing research
unassigned |
4
4
0 |
