EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.21.7 | Acantholysis |
6681540 |
Anti-cell surface pemphigus autoantibody stimulates plasminogen activator activity of human epidermal cells. A mechanism for the loss of epidermal cohesion and blister formation. |
causal interaction
ongoing research
unassigned |
4
4
0 |
| 3.4.21.7 | Acantholysis |
7510121 |
Cantharidin-induced acantholysis: adhesion molecules, proteases, and related proteins. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
3
2
0 |
| 3.4.21.7 | Acantholysis |
9347794 |
Pemphigus IgG induces expression of urokinase plasminogen activator receptor on the cell surface of cultured keratinocytes. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
1 |
| 3.4.21.7 | Acantholysis |
12675525 |
Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis. |
therapeutic application
unassigned |
3
0 |
| 3.4.21.7 | Acantholysis |
12930304 |
Urokinase plasminogen activator mRNA is induced by IL-1alpha and TNF-alpha in in vitro acantholysis. |
causal interaction
unassigned |
2
0 |
| 3.4.21.7 | Acidosis |
9488672 |
Histidine-proline-rich glycoprotein as a plasma pH sensor. Modulation of its interaction with glycosaminoglycans by ph and metals. |
diagnostic usage
therapeutic application
unassigned |
3
2
0 |
| 3.4.21.7 | Acidosis |
23354242 |
Recombinant tissue-type plasminogen activator-evoked hyperfibrinolysis is enhanced by acidosis and inhibited by hypothermia but still can be blocked by tranexamic acid. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
2
4
2
0 |
| 3.4.21.7 | Acquired Immunodeficiency Syndrome |
1398780 |
Dysregulated proteolysis in AIDS. |
diagnostic usage
ongoing research
unassigned |
4
3
0 |
| 3.4.21.7 | Acquired Immunodeficiency Syndrome |
9856830 |
Wound fluid from venous leg ulcers degrades plasminogen and reduces plasmin generation by keratinocytes. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
2
3
0 |
| 3.4.21.7 | Acquired Immunodeficiency Syndrome |
22124123 |
Haemophilus influenzae uses the surface protein E to acquire human plasminogen and to evade innate immunity. |
causal interaction
unassigned |
2
0 |
