EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.7.12.2 | Adenocarcinoma |
25601637 |
A subset of metastatic pancreatic ductal adenocarcinomas depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling. |
therapeutic application
unassigned |
1
0 |
| 2.7.12.2 | Adenocarcinoma |
28454307 |
miR-141 promotes colon cancer cell proliferation by inhibiting MAP2K4. |
diagnostic usage
ongoing research
unassigned |
4
4
0 |
| 2.7.12.2 | Adenocarcinoma |
29961751 |
Effects of 3-Tetrazolyl Methyl-3-Hydroxy-Oxindole Hybrid (THOH) on Cell Proliferation, Apoptosis, and G2/M Cell Cycle Arrest Occurs by Targeting Platelet-Derived Growth Factor D (PDGF-D) and the MEK/ERK Signaling Pathway in Human Lung Cell Lines SK-LU-1, A549, and A-427. |
therapeutic application
unassigned |
1
0 |
| 2.7.12.2 | Adenocarcinoma |
30401712 |
Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes. |
causal interaction
unassigned |
1
0 |
| 2.7.12.2 | Adenocarcinoma |
30445932 |
BKCa participates in E2 inducing endometrial adenocarcinoma by activating MEK/ERK pathway. |
causal interaction
diagnostic usage
ongoing research
unassigned |
2
3
2
0 |
| 2.7.12.2 | Adenocarcinoma |
31885544 |
HAVCR1 Affects the MEK/ERK Pathway in Gastric Adenocarcinomas and Influences Tumor Progression and Patient Outcome. |
causal interaction
diagnostic usage
ongoing research
unassigned |
2
3
4
0 |
| 2.7.12.2 | Adenocarcinoma |
32762399 |
A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers. |
causal interaction
unassigned |
1
0 |
| 2.7.12.2 | Adenocarcinoma of Lung |
21896780 |
Map2k4 functions as a tumor suppressor in lung adenocarcinoma and inhibits tumor cell invasion by decreasing peroxisome proliferator-activated receptor ?2 expression. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
1
0 |
| 2.7.12.2 | Adenocarcinoma of Lung |
25273224 |
Clinicopathologic features and outcomes of patients with lung adenocarcinomas harboring BRAF mutations in the Lung Cancer Mutation Consortium. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
1
1
1 |
| 2.7.12.2 | Adenocarcinoma of Lung |
27474067 |
Luteolin exerts pro-apoptotic effect and anti-migration effects on A549 lung adenocarcinoma cells through the activation of MEK/ERK signaling pathway. |
ongoing research
therapeutic application
unassigned |
3
1
0 |
