EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level  |
|---|
    2.6.1.16 | Insulin Resistance |
1743436 |
New insights into the metabolic regulation of insulin action and insulin resistance: role of glucose and amino acids. |
causal interaction
unassigned |
1
0 |
| 2.6.1.16 | Insulin Resistance |
10067838 |
Mechanism of hexosamine-induced insulin resistance in transgenic mice overexpressing glutamine:fructose-6-phosphate amidotransferase: decreased glucose transporter GLUT4 translocation and reversal by treatment with thiazolidinedione. |
causal interaction
therapeutic application
unassigned |
1
3
0 |
| 2.6.1.16 | Insulin Resistance |
11167021 |
Cloning and characterization of mouse glutamine:fructose-6-phosphate amidotransferase 2 gene promoter. |
causal interaction
unassigned |
1
0 |
| 2.6.1.16 | Muscular Diseases |
26501342 |
Global N-linked Glycosylation is Not Significantly Impaired in Myoblasts in Congenital Myasthenic Syndromes Caused by Defective Glutamine-Fructose-6-Phosphate Transaminase 1 (GFPT1). |
causal interaction
ongoing research
therapeutic application
unassigned |
1
2
1
0 |
| 2.6.1.16 | Muscular Dystrophies |
26501342 |
Global N-linked Glycosylation is Not Significantly Impaired in Myoblasts in Congenital Myasthenic Syndromes Caused by Defective Glutamine-Fructose-6-Phosphate Transaminase 1 (GFPT1). |
causal interaction
ongoing research
therapeutic application
unassigned |
1
2
1
0 |
| 2.6.1.16 | Myasthenic Syndromes, Congenital |
28712002 |
Mutations in GFPT1-related congenital myasthenic syndromes are associated with synaptic morphological defects and underlie a tubular aggregate myopathy with synaptopathy. |
causal interaction
unassigned |
1
0 |
| 2.6.1.16 | Neoplasms |
30912436 |
Emerging Anticancer Activity of Candidal Glucoseamine-6-Phosphate Synthase Inhibitors upon Nanoparticle-Mediated Delivery. |
ongoing research
therapeutic application
unassigned |
4
1
0 |
| 2.6.1.16 | Pancreatic Neoplasms |
27996048 |
High expression of GFAT1 predicts poor prognosis in patients with pancreatic cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
2
1 |
| 2.6.1.16 | Diabetes Complications |
17379537 |
Expression and purification of active human internal His(6)-tagged L-glutamine: D-Fructose-6P amidotransferase I. |
ongoing research
unassigned |
2
0 |
| 2.6.1.16 | Insulin Resistance |
16555472 |
Effect of sucrose and saturated-fat diets on mRNA levels of genes limiting muscle fatty acid and glucose supply in rats. |
causal interaction
unassigned |
2
0 |
