EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
2.6.1.16 | Diabetes Mellitus, Type 2 |
14764791 |
Common variants in glutamine:fructose-6-phosphate amidotransferase 2 (GFPT2) gene are associated with type 2 diabetes, diabetic nephropathy, and increased GFPT2 mRNA levels. |
causal interaction unassigned |
3 0 |
2.6.1.16 | Diabetes Mellitus, Type 2 |
17024311 |
Effect of +36T>C in intron 1 on the glutamine: fructose-6-phosphate amidotransferase 1 gene and its contribution to type 2 diabetes in different populations. |
diagnostic usage ongoing research therapeutic application unassigned |
3 4 1 0 |
2.6.1.16 | Diabetes Mellitus, Type 2 |
17379537 |
Expression and purification of active human internal His(6)-tagged L-glutamine: D-Fructose-6P amidotransferase I. |
ongoing research unassigned |
2 0 |
2.6.1.16 | Diabetes Mellitus, Type 2 |
17574229 |
Glutamine fructose-6-phosphate amidotransferase (GFAT) gene expression and activity in patients with type 2 diabetes: inter-relationships with hyperglycaemia and oxidative stress. |
causal interaction ongoing research therapeutic application unassigned |
1 3 1 0 |
2.6.1.16 | Diabetes Mellitus, Type 2 |
19059404 |
Structural analysis of human glutamine:fructose-6-phosphate amidotransferase, a key regulator in type 2 diabetes. |
ongoing research unassigned |
2 0 |
2.6.1.16 | Diabetes Mellitus, Type 2 |
23767808 |
Glutamine: fructose-6-phosphate amidotransferase (GFAT): homology modelling and designing of new inhibitors using pharmacophore and docking based hierarchical virtual screening protocol. |
unassigned |
0 |
2.6.1.16 | Diabetic Angiopathies |
12802498 |
Glutamine:fructose-6-phosphate aminotransferase enzyme activity is necessary for the induction of TGF-beta1 and fibronectin expression in mesangial cells. |
therapeutic application unassigned |
1 0 |
2.6.1.16 | Diabetic Nephropathies |
10997922 |
Overexpression of GFAT activates PAI-1 promoter in mesangial cells. |
unassigned |
0 |
2.6.1.16 | Esophageal Neoplasms |
32229685 |
LncRNA ELFN1-AS1 promotes esophageal cancer progression by up-regulating GFPT1 via sponging miR-183-3p. |
ongoing research unassigned |
1 0 |
2.6.1.16 | Glioblastoma |
30771196 |
Mammalian Target of Rapamycin 2 (MTOR2) and C-MYC Modulate Glucosamine-6-Phosphate Synthesis in Glioblastoma (GBM) Cells Through Glutamine: Fructose-6-Phosphate Aminotransferase 1 (GFAT1). |
causal interaction ongoing research unassigned |
4 1 0 |