EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
2.1.1.56 | Breast Neoplasms |
30991934 |
Oncogenic PIK3CA mutations increase dependency on the mRNA cap methyltransferase, RNMT, in breast cancer cells. |
causal interaction ongoing research therapeutic application unassigned |
3 2 4 0 |
2.1.1.56 | Bronchitis |
20573827 |
The cellular RNA helicase DDX1 interacts with coronavirus nonstructural protein 14 and enhances viral replication. |
diagnostic usage therapeutic application unassigned |
3 1 0 |
2.1.1.56 | Coinfection |
24778195 |
A highly conserved region between amino acids 221 and 266 of dengue virus non-structural protein 1 is a major epitope region in infected patients. |
causal interaction diagnostic usage ongoing research unassigned |
1 3 2 0 |
2.1.1.56 | Coinfection |
33245437 |
Use of whole blood over plasma enhances the detection of dengue virus RNA: possible utility in dengue vaccine trials. |
diagnostic usage unassigned |
1 0 |
2.1.1.56 | Coma |
31891331 |
Thrombotic thrombocytopenic purpura in a 2.5-year-old boy with dengue infection: a rare complication. |
causal interaction unassigned |
3 0 |
2.1.1.56 | COVID-19 |
32567979 |
Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19. |
therapeutic application unassigned |
4 0 |
2.1.1.56 | COVID-19 |
32907334 |
Repurposing of FDA-Approved Toremifene to Treat COVID-19 by Blocking the Spike Glycoprotein and NSP14 of SARS-CoV-2. |
causal interaction therapeutic application unassigned |
3 4 0 |
2.1.1.56 | COVID-19 |
33619486 |
Probing the SAM Binding Site of SARS-CoV-2 nsp14 in vitro Using SAM Competitive Inhibitors Guides Developing Selective bi-substrate Inhibitors. |
causal interaction therapeutic application unassigned |
3 4 0 |
2.1.1.56 | COVID-19 |
34192965 |
Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors. |
causal interaction therapeutic application unassigned |
3 4 0 |
2.1.1.56 | COVID-19 |
34198328 |
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase. |
causal interaction therapeutic application unassigned |
4 4 0 |