EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
1.11.2.2 | Acute Kidney Injury |
23229164 |
Churg-Strauss syndrome presenting with acute kidney injury in a case of primary focal segmental glomerulosclerosis. |
causal interaction diagnostic usage unassigned |
2 1 0 |
1.11.2.2 | Acute Kidney Injury |
24412858 |
Chronic ethanol ingestion induces oxidative kidney injury through taurine-inhibitable inflammation. |
causal interaction unassigned |
1 0 |
1.11.2.2 | Acute Kidney Injury |
25323773 |
Inhibition of glycogen synthase kinase-3? attenuates acute kidney injury in sodium taurocholate?induced severe acute pancreatitis in rats. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 4 4 2 |
1.11.2.2 | Acute Kidney Injury |
26720402 |
Inflammatory PAF Receptor Signaling Initiates Hedgehog Signaling and Kidney Fibrogenesis During Ethanol Consumption. |
causal interaction unassigned |
1 0 |
1.11.2.2 | Acute Kidney Injury |
33284091 |
Myostatin deficiency not only prevents muscle wasting but also improves survival in septic mice. |
unassigned |
0 |
1.11.2.2 | Acute Lung Injury |
2982979 |
Myeloperoxidase-induced inactivation of alpha 1-antiprotease in hamsters. |
causal interaction therapeutic application unassigned |
2 1 0 |
1.11.2.2 | Acute Lung Injury |
7949627 |
Clinical significance of measuring myeloperoxidase, thiobarbituric acid reactive material and 7S collagen in plasma of patients with adult respiratory distress syndrome. |
causal interaction diagnostic usage ongoing research unassigned |
4 3 3 0 |
1.11.2.2 | Acute Lung Injury |
8230889 |
[Measurement of myeloperoxidase and thiobarbituric acid-reactive material in plasma and bronchoalveolar lavage in E. coli-induced acute lung injury] |
diagnostic usage ongoing research unassigned |
3 3 0 |
1.11.2.2 | Acute Lung Injury |
9553712 |
Purification of myeloperoxidase from equine polymorphonuclear leucocytes. |
diagnostic usage therapeutic application unassigned |
3 1 0 |
1.11.2.2 | Acute Lung Injury |
11940761 |
Effects of inhaled nitric oxide in a mouse model of sepsis-induced acute lung injury. |
causal interaction diagnostic usage unassigned |
4 2 0 |
1.11.2.2 | Acute Lung Injury |
15020295 |
Myeloperoxidase deficiency enhances inflammation after allogeneic marrow transplantation. |
causal interaction unassigned |
3 0 |
1.11.2.2 | Acute Lung Injury |
16887102 |
Effective attenuation of acute lung injury in vivo and the formyl peptide-induced neutrophil activation in vitro by CYL-26z through the phosphoinositide 3-kinase gamma pathway. |
ongoing research therapeutic application unassigned |
2 1 0 |
1.11.2.2 | Acute Lung Injury |
18283562 |
The involvement of nitric oxide, nitric oxide synthase, neutrophil elastase, myeloperoxidase and proinflammatory cytokines in the acute lung injury caused by phorbol myristate acetate. |
causal interaction diagnostic usage unassigned |
1 2 0 |
1.11.2.2 | Acute Lung Injury |
19010691 |
IL-10 deficiency augments acute lung but not liver injury in hemorrhagic shock. |
diagnostic usage ongoing research unassigned |
4 2 0 |
1.11.2.2 | Acute Lung Injury |
19483113 |
15-epi-lipoxin A4 inhibits myeloperoxidase signaling and enhances resolution of acute lung injury. |
causal interaction unassigned |
1 0 |
1.11.2.2 | Acute Lung Injury |
19783685 |
Critical role of IL-17RA in immunopathology of influenza infection. |
causal interaction unassigned |
4 0 |
1.11.2.2 | Acute Lung Injury |
19941153 |
Early administration of propofol protects against endotoxin-induced acute lung injury in rats by inhibiting the TGF-beta1-Smad2 dependent pathway. |
causal interaction diagnostic usage therapeutic application unassigned |
1 3 1 0 |
1.11.2.2 | Acute Lung Injury |
20154604 |
Therapeutic accessibility of caspase-mediated cell death as a key pathomechanism in indirect acute lung injury. |
causal interaction diagnostic usage therapeutic application unassigned |
3 1 4 0 |
1.11.2.2 | Acute Lung Injury |
20638132 |
Heme oxygenase-1 upregulation improves lipopolysaccharide-induced acute lung injury involving suppression of macrophage migration inhibitory factor. |
causal interaction ongoing research therapeutic application unassigned |
4 2 1 0 |
1.11.2.2 | Acute Lung Injury |
20850789 |
Heme Oxygenase-1 Mediates the Protective Effects of Ischemic Preconditioning on Mitigating Lung Injury Induced by Lower Limb Ischemia-Reperfusion in Rats. |
causal interaction ongoing research unassigned |
4 2 0 |
1.11.2.2 | Acute Lung Injury |
21396178 |
Long-term Simvastatin Administration Attenuates Lung Injury and Oxidative Stress in Murine Acute Lung Injury Models Induced by Oleic Acid and Endotoxin. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 1 2 2 |
1.11.2.2 | Acute Lung Injury |
21436719 |
Intensive Insulin Treatment Attenuates Burn-Initiated Acute Lung Injury in Rats: Role of the Protective Endothelium. |
diagnostic usage unassigned |
4 0 |
1.11.2.2 | Acute Lung Injury |
21875662 |
Cyptoporus polysaccharide prevents lipopolysaccharide-induced acute lung injury associated with down-regulating Toll-like receptor 2 expression. |
causal interaction ongoing research therapeutic application unassigned |
3 4 1 0 |
1.11.2.2 | Acute Lung Injury |
22265864 |
Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: Role for the adenosine A(2A) receptor. |
ongoing research unassigned |
2 0 |
1.11.2.2 | Acute Lung Injury |
22772811 |
p-Cymene protects mice against lipopolysaccharide-induced acute lung injury by inhibiting inflammatory cell activation. |
therapeutic application unassigned |
2 0 |
1.11.2.2 | Acute Lung Injury |
24412620 |
Zingerone attenuates lipopolysaccharide-induced acute lung injury in mice. |
causal interaction diagnostic usage unassigned |
4 3 0 |
1.11.2.2 | Acute Lung Injury |
24601225 |
Histone deacetylase inhibitors trichostatin A and suberoylanilide hydroxamic acid attenuate ventilator-induced lung injury. |
causal interaction diagnostic usage ongoing research therapeutic application |
3 4 4 1 |
1.11.2.2 | Acute Lung Injury |
24841888 |
Cyanidin-3-O-?-glucoside ameliorates lipopolysaccharide-induced acute lung injury by reducing TLR4 recruitment into lipid rafts. |
causal interaction therapeutic application unassigned |
3 2 0 |
1.11.2.2 | Acute Lung Injury |
25243152 |
Agmatine protects against zymosan-induced acute lung injury in mice by inhibiting NF-?B-mediated inflammatory response. |
therapeutic application unassigned |
2 0 |
1.11.2.2 | Acute Lung Injury |
25250598 |
High-altitude pulmonary edema can be prevented by heat shock protein 70-mediated hyperbaric oxygen preconditioning. |
causal interaction diagnostic usage ongoing research therapeutic application |
3 3 2 2 |
1.11.2.2 | Acute Lung Injury |
25845602 |
Formaldehyde inhalation during pregnancy abolishes the development of acute innate inflammation in offspring. |
causal interaction therapeutic application unassigned |
3 1 0 |
1.11.2.2 | Acute Lung Injury |
26232301 |
Smart imaging of acute lung injury: exploration of myeloperoxidase activity using in vivo endoscopic confocal fluorescence microscopy. |
ongoing research therapeutic application unassigned |
1 1 0 |
1.11.2.2 | Acute Lung Injury |
26495959 |
Absinthin attenuates LPS-induced ALI through MIP-1?-mediated inflammatory cell infiltration. |
causal interaction therapeutic application unassigned |
1 1 0 |
1.11.2.2 | Acute Lung Injury |
26610718 |
Hesperetin attenuates ventilator-induced acute lung injury through inhibition of NF-?B-mediated inflammation. |
causal interaction unassigned |
3 0 |
1.11.2.2 | Acute Lung Injury |
26710167 |
Pretreatment with the compound asperuloside decreases acute lung injury via inhibiting MAPK and NF-?B signaling in a murine model. |
ongoing research therapeutic application unassigned |
2 1 0 |
1.11.2.2 | Acute Lung Injury |
26781077 |
Hydrogen sulfide ameliorates acute lung injury induced by infrarenal aortic cross-clamping by inhibiting inflammation and angiopoietin 2 release. |
diagnostic usage ongoing research therapeutic application unassigned |
3 4 1 0 |
1.11.2.2 | Acute Lung Injury |
28558870 |
Synthesis and evaluation of 2-cyano-3, 12-dioxooleana-1, 9(11)-en-28-oate-13?, 28-olide as a potent anti-inflammatory agent for intervention of LPS-induced acute lung injury. |
ongoing research therapeutic application unassigned |
1 1 0 |
1.11.2.2 | Acute Lung Injury |
28808186 |
Oxygenation, inflammatory response and lung injury during one lung ventilation in rabbits using inspired oxygen fraction of 0.6 vs. 1.0. |
unassigned |
0 |
1.11.2.2 | Acute Lung Injury |
29351433 |
?-Nitrostyrene derivatives attenuate LPS-mediated acute lung injury via the inhibition of neutrophil-platelet interactions and NET release. |
ongoing research therapeutic application unassigned |
1 1 0 |
1.11.2.2 | Acute Lung Injury |
30174607 |
Andrographolide Sulfonate Attenuates Acute Lung Injury by Reducing Expression of Myeloperoxidase and Neutrophil-Derived Proteases in Mice. |
causal interaction ongoing research therapeutic application unassigned |
1 1 1 0 |
1.11.2.2 | Acute Lung Injury |
31072918 |
Ganoderic acid A attenuates lipopolysaccharide-induced lung injury in mice. |
unassigned |
0 |
1.11.2.2 | Acute Lung Injury |
32801831 |
NLRP3 Regulated CXCL12 Expression in Acute Neutrophilic Lung Injury. |
ongoing research therapeutic application unassigned |
3 1 0 |
1.11.2.2 | Adenocarcinoma |
14688711 |
Simultaneous progression of oxidative stress and angiogenesis in malignant transformation of Barrett esophagus. |
ongoing research unassigned |
4 0 |
1.11.2.2 | Adenocarcinoma |
18205184 |
Myeloperoxidase and superoxide dismutase polymorphisms are associated with an increased risk of developing pancreatic adenocarcinoma. |
causal interaction diagnostic usage unassigned |
4 3 0 |
1.11.2.2 | Adenocarcinoma |
25100294 |
Evaluation of a 4-protein serum biomarker panel-biglycan, annexin-A6, myeloperoxidase, and protein S100-A9 (B-AMP)-for the detection of esophageal adenocarcinoma. |
diagnostic usage unassigned |
1 0 |
1.11.2.2 | Adenocarcinoma |
25918191 |
Early detection of high oxidative activity in patients with adenomatous intestinal polyps and colorectal adenocarcinoma: myeloperoxidase and oxidized low-density lipoprotein in serum as new markers of oxidative stress in colorectal cancer. |
causal interaction diagnostic usage unassigned |
4 4 0 |
1.11.2.2 | Adenocarcinoma |
34249773 |
Changes in Microbial Community Composition Related to Sex and Colon Cancer by Nrf2 Knockout. |
causal interaction unassigned |
3 0 |
1.11.2.2 | Adenoma |
34117903 |
Comprehensive aptamer-based screen of 1317 proteins uncovers improved stool protein markers of colorectal cancer. |
causal interaction diagnostic usage ongoing research unassigned |
4 3 1 0 |
1.11.2.2 | Adenoma |
34249773 |
Changes in Microbial Community Composition Related to Sex and Colon Cancer by Nrf2 Knockout. |
causal interaction unassigned |
3 0 |
1.11.2.2 | Agammaglobulinemia |
1710723 |
[A spectrophotometric method of determining the myeloperoxidase activity in phagocytic cells] |
causal interaction diagnostic usage unassigned |
4 4 0 |
1.11.2.2 | Aggressive Periodontitis |
9151641 |
Myeloperoxidase isoform activities released by human neutrophils in response to dental and periodontal bacteria. |
causal interaction diagnostic usage therapeutic application unassigned |
3 3 1 0 |
1.11.2.2 | Aggressive Periodontitis |
10776935 |
The importance of data presentation regarding gingival crevicular fluid myeloperoxidase and elastase-like activity in periodontal disease and health status. |
diagnostic usage ongoing research unassigned |
2 3 0 |
1.11.2.2 | Aggressive Periodontitis |
12351672 |
Amplified crevicular leukocyte activity in aggressive periodontal disease. |
ongoing research therapeutic application unassigned |
1 1 0 |
1.11.2.2 | Aggressive Periodontitis |
16499716 |
Gingival crevicular fluid levels of calprotectin and myeloperoxidase during therapy for generalized aggressive periodontitis. |
therapeutic application unassigned |
1 0 |
1.11.2.2 | Aggressive Periodontitis |
20364045 |
Genetic variation of myeloperoxidase gene contributes to aggressive periodontitis: a preliminary association study in Turkish population. |
ongoing research unassigned |
1 0 |
1.11.2.2 | Aggressive Periodontitis |
21976840 |
Myeloperoxidase staining in the diagnosis of aggressive periodontitis. |
diagnostic usage therapeutic application unassigned |
4 1 0 |
1.11.2.2 | Aggressive Periodontitis |
24799321 |
Serum and salivary matrix metalloproteinases, neutrophil elastase, myeloperoxidase in patients with chronic or aggressive periodontitis. |
causal interaction diagnostic usage ongoing research unassigned |
1 2 4 0 |
1.11.2.2 | Aggressive Periodontitis |
25939876 |
Evaluation of Local and Systemic Levels of Interleukin-17, Interleukin-23, and Myeloperoxidase in Response to Periodontal Therapy in Patients with Generalized Aggressive Periodontitis. |
diagnostic usage ongoing research therapeutic application unassigned |
4 3 3 0 |
1.11.2.2 | Agranulocytosis |
190672 |
Serum myeloperoxidase and lactoferrin in neutropenia. |
causal interaction diagnostic usage ongoing research therapeutic application |
1 4 1 1 |
1.11.2.2 | Agranulocytosis |
1346986 |
Comparative metabolism and covalent binding of procainamide by human leukocytes. |
causal interaction unassigned |
4 0 |
1.11.2.2 | Agranulocytosis |
3031000 |
Interleukin-1-induced granulocytopenia and pulmonary leukostasis in rabbits. |
causal interaction unassigned |
4 0 |
1.11.2.2 | Agranulocytosis |
7726734 |
Peroxidase-catalysed oxidation of different dibenzazepine derivatives. |
unassigned |
0 |
1.11.2.2 | Agranulocytosis |
8385460 |
Carbamazepine metabolism to a reactive intermediate by the myeloperoxidase system of activated neutrophils. |
causal interaction therapeutic application unassigned |
1 1 0 |
1.11.2.2 | Agranulocytosis |
9038241 |
Activation of CGS 12094 (prinomide metabolite) to 1,4-benzoquinone by myeloperoxidase: implications for human idiosyncratic agranulocytosis. |
therapeutic application unassigned |
1 0 |
1.11.2.2 | Agranulocytosis |
11147929 |
Clozapine-induced agranulocytosis and hereditary polymorphisms of clozapine metabolizing enzymes: no association with myeloperoxidase and cytochrome P4502D6. |
unassigned |
0 |
1.11.2.2 | Agranulocytosis |
15538122 |
Impact of myeloperoxidase and NADPH-oxidase polymorphisms in drug-induced agranulocytosis. |
therapeutic application unassigned |
1 0 |
1.11.2.2 | Agranulocytosis |
17602675 |
Aminoglutethimide-induced protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis. |
causal interaction therapeutic application unassigned |
1 4 0 |
1.11.2.2 | Agranulocytosis |
18489081 |
Procainamide, but not N-acetylprocainamide, induces protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis. |
causal interaction therapeutic application unassigned |
1 1 0 |
1.11.2.2 | Agranulocytosis |
21671642 |
Drug-induced protein free radical formation is attenuated by unsaturated Fatty acids by scavenging drug-derived phenyl radical metabolites. |
causal interaction therapeutic application unassigned |
3 3 0 |
1.11.2.2 | Agranulocytosis |
24588327 |
Involvement of Myeloperoxidase and NADPH Oxidase in the Covalent Binding of Amodiaquine and Clozapine to Neutrophils: Implications for Drug-Induced Agranulocytosis. |
therapeutic application unassigned |
1 0 |
1.11.2.2 | Agranulocytosis |
27824551 |
Cocaine-Induced Vasculitis. |
causal interaction unassigned |
3 0 |
1.11.2.2 | Airway Obstruction |
8239158 |
Airway inflammation in smokers with nonobstructive and obstructive chronic bronchitis. |
causal interaction unassigned |
3 0 |
1.11.2.2 | Airway Obstruction |
17042382 |
Myeloperoxidase concentration in bronchoalveolar lavage fluid from healthy horses and those with recurrent airway obstruction. |
diagnostic usage ongoing research unassigned |
2 2 0 |
1.11.2.2 | Airway Obstruction |
22089200 |
Combined recombinant human activated protein C and ceftazidime prevent the onset of acute respiratory distress syndrome in severe sepsis. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 2 4 3 |
1.11.2.2 | Alveolar Bone Loss |
19274705 |
Protective effect of locally applied carvacrol gel on ligature-induced periodontitis in rats: a tapping mode AFM study. |
unassigned |
0 |
1.11.2.2 | Alveolar Bone Loss |
19778332 |
Short-term induction of thrombocytopenia delays periodontal healing in rats with periodontal disease: participation of endostatin and vascular endothelial growth factor. |
causal interaction ongoing research therapeutic application unassigned |
1 1 1 0 |
1.11.2.2 | Alveolar Bone Loss |
20820824 |
Nafamostat mesilate, a potent tryptase inhibitor, modulates periodontitis in rats. |
diagnostic usage ongoing research therapeutic application unassigned |
4 4 3 0 |
1.11.2.2 | Alveolar Bone Loss |
21118355 |
Effects of calcium gluconate on experimental periodontitis and alveolar bone loss in rats. |
diagnostic usage ongoing research unassigned |
1 3 0 |
1.11.2.2 | Alveolar Bone Loss |
22780690 |
Effects of Polycan, a ?-glucan, on experimental periodontitis and alveolar bone loss in Sprague-Dawley rats. |
diagnostic usage ongoing research unassigned |
3 3 0 |
1.11.2.2 | Alveolar Bone Loss |
26832833 |
Effects of Melatonin on Oxidative Stress Index and Alveolar Bone Loss in Diabetic Rats With Periodontitis. |
diagnostic usage ongoing research unassigned |
4 3 0 |
1.11.2.2 | Alveolar Bone Loss |
27110759 |
The Effects of Topical Application of Polycal (a 2:98 (g/g) Mixture of Polycan and Calcium Gluconate) on Experimental Periodontitis and Alveolar Bone Loss in Rats. |
diagnostic usage ongoing research unassigned |
1 4 0 |
1.11.2.2 | Alveolar Bone Loss |
27666673 |
Decrease of Pericytes is Associated With Liver Disease Caused by Ligature-Induced Periodontitis in Rats. |
diagnostic usage ongoing research unassigned |
2 3 0 |
1.11.2.2 | Alveolar Bone Loss |
28419499 |
Periodontitis changes renal structures by oxidative stress and lipid peroxidation. |
diagnostic usage therapeutic application unassigned |
2 1 0 |
1.11.2.2 | Alveolar Bone Loss |
28504459 |
Steatosis caused by experimental periodontitis is reversible after removal of ligature in rats. |
ongoing research unassigned |
1 0 |
1.11.2.2 | Alveolar Bone Loss |
28964840 |
Orabase formulation with cashew gum polysaccharide decreases inflammatory and bone loss hallmarks in experimental periodontitis. |
causal interaction unassigned |
3 0 |
1.11.2.2 | Alveolar Bone Loss |
29680842 |
One or two ligatures inducing periodontitis are sufficient to cause fatty liver. |
diagnostic usage ongoing research unassigned |
2 1 0 |
1.11.2.2 | Alveolar Bone Loss |
30926484 |
Sulfated polysaccharides from the marine algae Gracilaria caudata prevent tissue damage caused by ligature-induced periodontitis. |
diagnostic usage unassigned |
1 0 |
1.11.2.2 | Alveolar Bone Loss |
32563778 |
A semi-synthetic flavonoid from Bauhinia pulchella stem attenuates inflammatory osteolysis in periodontitis in rats: Impact on cytokine levels, oxidative stress, and RANK/RANKL/OPG pathway. |
unassigned |
0 |
1.11.2.2 | Alzheimer Disease |
8762192 |
Apolipoprotein E is highly susceptible to oxidation by myeloperoxidase, an enzyme present in the brain. |
causal interaction diagnostic usage unassigned |
1 1 0 |
1.11.2.2 | Alzheimer Disease |
9918702 |
Myeloperoxidase polymorphism is associated with gender specific risk for Alzheimer's disease. |
causal interaction diagnostic usage therapeutic application unassigned |
4 2 2 0 |
1.11.2.2 | Alzheimer Disease |
11161635 |
Association between Alzheimer's disease and a functional polymorphism in the Myeloperoxidase gene. |
causal interaction ongoing research unassigned |
3 4 0 |
1.11.2.2 | Alzheimer Disease |
12052532 |
The myeloperoxidase gene in Alzheimer's disease: a case-control study and meta-analysis. |
causal interaction ongoing research therapeutic application unassigned |
4 4 1 0 |
1.11.2.2 | Alzheimer Disease |
12946561 |
Myeloperoxidase G-463A polymorphism and Alzheimer's disease in the ApoEurope study. |
ongoing research unassigned |
2 0 |
1.11.2.2 | Alzheimer Disease |
14668325 |
Peroxisome proliferator-activated receptor gamma ligands regulate myeloperoxidase expression in macrophages by an estrogen-dependent mechanism involving the -463GA promoter polymorphism. |
causal interaction therapeutic application unassigned |
4 1 0 |
1.11.2.2 | Alzheimer Disease |
15255951 |
Neuronal expression of myeloperoxidase is increased in Alzheimer's disease. |
causal interaction unassigned |
4 0 |
1.11.2.2 | Alzheimer Disease |
16484808 |
No Genetic Association between the Myeloperoxidase Gene -463 Polymorphism and Estrogen Receptor-alpha Gene Polymorphisms and Japanese Sporadic Alzheimer's Disease. |
causal interaction ongoing research unassigned |
4 2 0 |
1.11.2.2 | Alzheimer Disease |
16641309 |
Myeloperoxidase polymorphism and cognitive decline in older adults in the Health, Aging, and Body Composition Study. |
causal interaction unassigned |
4 0 |
1.11.2.2 | Alzheimer Disease |
17045922 |
Oxidized plasma high-density lipoprotein is decreased in Alzheimer's disease. |
causal interaction unassigned |
4 0 |
1.11.2.2 | Alzheimer Disease |
19059911 |
Aberrant expression of myeloperoxidase in astrocytes promotes phospholipid oxidation and memory deficits in a mouse model of Alzheimer disease. |
ongoing research unassigned |
2 0 |
1.11.2.2 | Alzheimer Disease |
24217274 |
Increased myeloperoxidase plasma levels in patients with Alzheimer's disease. |
causal interaction diagnostic usage unassigned |
4 4 0 |