EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category  |
Confidence Level |
|---|
   3.4.17.23 | Neoplasms |
15537383 |
The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
1 |
| 3.4.17.23 | Neoplasms |
17079440 |
TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
3
3
2
0 |
| 3.4.17.23 | Neoplasms |
17334351 |
A variant TMPRSS2 isoform and ERG fusion product in prostate cancer with implications for molecular diagnosis. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
3
1
0 |
| 3.4.17.23 | Neoplasms |
17804708 |
Heterogeneity of TMPRSS2 gene rearrangements in multifocal prostate adenocarcinoma: molecular evidence for an independent group of diseases. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
1
2
1
0 |
| 3.4.17.23 | Neoplasms |
18338334 |
The androgen-regulated type II serine protease TMPRSS2 is differentially expressed and mislocalized in prostate adenocarcinoma. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
4
4
0 |
| 3.4.17.23 | Neoplasms |
19212105 |
Decreased expression of Angiotensin-converting enzyme 2 in pancreatic ductal adenocarcinoma is associated with tumor progression. |
causal interaction
unassigned |
4
0 |
| 3.4.17.23 | Neoplasms |
19242826 |
Association of TMPRSS2 and KLK11 gene expression levels with clinical progression of human prostate cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
4
3 |
| 3.4.17.23 | Neoplasms |
19759332 |
Selective and Specific Regulation of Ectodomain Shedding of Angiotensin-converting Enzyme 2 by Tumor Necrosis Factor {alpha}-converting Enzyme. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
| 3.4.17.23 | Neoplasms |
19851091 |
Recombinant angiotensin-converting enzyme 2 improves pulmonary blood flow and oxygenation in lipopolysaccharide-induced lung injury in piglets. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
1
3
4 |
| 3.4.17.23 | Neoplasms |
20382709 |
TMPRSS2, a Serine Protease Expressed in the Prostate on the Apical Surface of Luminal Epithelial Cells and Released into Semen in Prostasomes, Is Misregulated in Prostate Cancer Cells. |
causal interaction
ongoing research
unassigned |
3
3
0 |
