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EC Number
IC50 Value
IC50 Value Maximum
Inhibitor
Commentary
Reference
4.3.3.7
0.0325
-
2-oxopimelate
pH 7.4, 37°C
746457
4.3.3.7
0.033
-
L-lysine
pH 8.0, 30°C
749039
4.3.3.7
0.053
-
L-lysine
-
702445
4.3.3.7
0.065
-
(S)-lysine
pH and temperature not specified in the publication
729237
4.3.3.7
0.068
-
(S)-lysine
30°C, pH not specified in the publication
746463
4.3.3.7
0.21
-
L-lysine
wild-type DHDPS
702036
4.3.3.7
0.22
-
L-lysine
C-terminal truncated DHDPS (H225*)
702036
4.3.3.7
14
-
dimethyl chelidamate
IC50: 14 mM. 99% inhibition at 50 mM, noncompetitive with respect to both substrates
664304
4.3.3.7
20
-
(2R,6S)-piperidine-2,6-dicarboxylic acid
IC50: 20 mM, 83% inhibition at 50 mM
664304
4.3.3.7
20
-
dipicolinic acid
IC50: 20 mM, competitive inhibitor
664304
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