EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
   3.4.24.B12 | -999 |
- |
2-[4-(benzyloxy)phenyl]-3-oxoisoindoline-4-carboxylic acid |
IC25-value: 0.0075 mM, 37°C, pH and temperature not specified in the publication, plateau inhibition at about 50% |
708129 |
| 3.4.24.B12 | -999 |
- |
2-[4-(benzyloxy)phenyl]-N-hydroxy-3-oxoisoindoline-4-carboxamide |
IC25-value: 0.0025 mM, 37°C, pH and temperature not specified in the publication, plateau inhibition at about 50% |
708129 |
| 3.4.24.B12 | -999 |
- |
more |
inhibitors which show strong potency of IC50 with excellent selectivity over MMP-1 and TACE |
691315 |
| 3.4.24.B12 | 0.0000014 |
- |
(2R,5R)-1-([4-[(2,4-dichlorobenzyl)oxy]phenyl]sulfonyl)-N,5-dihydroxy-3,3-dimethylpiperidine-2-carboxamide |
37°C, pH and temperature not specified in the publication |
708129 |
| 3.4.24.B12 | 0.0000038 |
- |
TIMP-3 |
in 100 mM Tris-HCl, 100 mM NaCl, 0.01 mM CaCl2, 0.05% Brij, pH 7.5 |
680903 |
| 3.4.24.B12 | 0.000004 |
- |
N-[[(4S)-4-(1-methylimidazol-2-yl)-2,5-dioxo-imidazolidin-4-yl]methyl]-5-(trifluoromethyl)benzofuran-2-carboxamide |
pH 7.5, 22°C |
734452 |
| 3.4.24.B12 | 0.0000074 |
- |
(1S,2R,3R)-1-([[5-(4-chloro-1H-pyrazol-1-yl)thiophen-2-yl]sulfonyl]amino)-2-methyl-3-phenylcyclopropanecarboxylate |
pH and temperature not specified in the publication |
707686 |
| 3.4.24.B12 | 0.00001 |
- |
(1S,2R)-1-([[5-(4-chlorophenyl)thiophen-2-yl]sulfonyl]amino)-2-methyl-2-phenylcyclopropanecarboxylate |
pH and temperature not specified in the publication |
707686 |
| 3.4.24.B12 | 0.000017 |
- |
(3R)-N2-(cyclopropylmethyl)-N1-hydroxy-3-(3-hydroxybenzyl)-N4-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-L-aspartamide |
pH 7.5, 37°C |
709044 |
| 3.4.24.B12 | 0.000021 |
- |
(1S,2R,3R)-1-([[5-(4-chlorophenyl)thiophen-2-yl]sulfonyl]amino)-2-methyl-3-phenylcyclopropanecarboxylate |
pH and temperature not specified in the publication |
707686 |
