EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
   3.4.22.70 | -999 |
- |
more |
IC50 for aaptamine is 0.0235 mg/ml, IC50 for isoaaptamine is 0.0037 mg/ml, IC50 for demethylaaptamine is 0.0172 mg/ml, IC50 for demethyloxyaaptamine is 0.0201 mg/ml, IC50 for berberine chloride is 0.0087 mg/ml |
678685 |
| 3.4.22.70 | 0.0002 |
- |
4-ethoxy-2-phenyl-5-sulfanylpyridazin-3(2H)-one |
in 20 mM HEPES, 5 mM CaCl2, 0.05% (v/v) Tween-20, pH 7.5, at 25°C |
707732 |
| 3.4.22.70 | 0.001 |
- |
4-chloro-5-ethoxy-2-phenylpyridazin-3-one |
in 20 mM HEPES, 5 mM CaCl2, 0.05% (v/v) Tween-20, pH 7.5, at 25°C |
707732 |
| 3.4.22.70 | 0.00106 |
- |
divinyl sulfone |
IC50: 0.00106 mM, irreversible |
665297 |
| 3.4.22.70 | 0.00113 |
- |
cis-1,2-bis(phenylsulfonyl)ethylene |
IC50: 0.00113 mM, irreversible |
665297 |
| 3.4.22.70 | 0.0014 |
- |
4-(ethylsulfanyl)-2-phenyl-5-sulfanylpyridazin-3(2H)-one |
in 20 mM HEPES, 5 mM CaCl2, 0.05% (v/v) Tween-20, pH 7.5, at 25°C |
707732 |
| 3.4.22.70 | 0.0015 |
- |
bis(4-ethoxy-2-phenyl-5-pyridazyl)disulfide |
in 20 mM HEPES, 5 mM CaCl2, 0.05% (v/v) Tween-20, pH 7.5, at 25°C |
707732 |
| 3.4.22.70 | 0.0031 |
- |
5-ethoxy-2-(3-methylphenyl)-4-sulfanylpyridazin-3(2H)-one |
in 20 mM HEPES, 5 mM CaCl2, 0.05% (v/v) Tween-20, pH 7.5, at 25°C |
707732 |
| 3.4.22.70 | 0.0033 |
- |
4-(ethylsulfanyl)-2-(3-methylphenyl)-5-sulfanylpyridazin-3(2H)-one |
in 20 mM HEPES, 5 mM CaCl2, 0.05% (v/v) Tween-20, pH 7.5, at 25°C |
707732 |
| 3.4.22.70 | 0.00339 |
- |
N'-(3-(4-fluoro-3-oxobenzo[d]isothiazol-2(3H)-yl)propanoyl)adamantane-1-carbohydrazide |
pH 7.5, 37°C, recombinant His6-tagged truncated enzyme mutant variant SrtADELTA74 |
731478 |
