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EC Number IC50 Value IC50 Value Maximum Inhibitor Commentary Reference
Show all pathways known for 2.7.7.3Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.30.000000065 - 2'-[(1S,2S)-2-[(3,4-dichlorobenzyl)carbamoyl]cyclohexyl]-6'-ethyl-4-hydroxy-6-oxo-1,6-dihydro-2,4'-bipyrimidine-5-carboxamide pH 7.0, 22°C, recombinant enzyme 737460
Show all pathways known for 2.7.7.3Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.30.00000013 - 3-[3-(2-[(1S,2S)-2-[(3,4-dichlorobenzyl)carbamoyl]cyclohexyl]-6-ethylpyrimidin-4-yl)-1,2,4-oxadiazol-5-yl]propanoic acid pH 7.0, 22°C, recombinant enzyme 737460
Show all pathways known for 2.7.7.3Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.30.00000041 - 3-[3-(2-[(1S,2S)-2-[(3,4-dichlorobenzyl)carbamoyl]cyclohexyl]-6-ethylpyrimidin-4-yl)-1,2,4-oxadiazol-5-yl]propanoic acid pH 7.0, 22°C, recombinant enzyme 737460
Show all pathways known for 2.7.7.3Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.30.00000087 - 2'-[(1S,2S)-2-[(3,4-dichlorobenzyl)carbamoyl]cyclohexyl]-6'-ethyl-4-hydroxy-6-oxo-1,6-dihydro-2,4'-bipyrimidine-5-carboxamide pH 7.0, 22°C, recombinant enzyme 737460
Show all pathways known for 2.7.7.3Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.30.0000011 - (3R)-3-(3-chlorophenyl)-3-[(7-[[2-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]amino]-5-methyl-1H-imidazo[4,5-b]pyridin-2-yl)amino]propanenitrile pH 7.5, temperature not specified in the publication 761675
Show all pathways known for 2.7.7.3Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.30.0000012 - 1-[5-[(2-[[(1R)-1-(3-chlorophenyl)ethyl]amino]-5-methyl-1H-imidazo[4,5-b]pyridin-7-yl)amino]-2,3-dihydro-1H-indol-1-yl]ethan-1-one pH 7.5, temperature not specified in the publication 761675
Show all pathways known for 2.7.7.3Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.30.0000024 - methyl 4-(3-[(1R)-2-cyano-1-[(5-methyl-1H-imidazo[4,5-b]pyridin-2-yl)amino]ethyl]benzene-1-sulfonyl)piperidine-1-carboxylate pH 7.5, temperature not specified in the publication 761675
Show all pathways known for 2.7.7.3Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.30.0000025 - methyl (R)-4-(3-(2-cyano-1-((5-methyl-1H-imidazo[4,5-b]pyridin-2-yl)amino)ethyl)benzyl)piperidine-1-carboxylate pH 7.5, temperature not specified in the publication 761675
Show all pathways known for 2.7.7.3Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.30.0000026 - 2'-[(1S,2S)-2-[(3,4-dichlorobenzyl)carbamoyl]cyclohexyl]-6'-ethyl-4-hydroxy-6-oxo-1,6-dihydro-2,4'-bipyrimidine-5-carboxamide pH 7.0, 22°C, recombinant enzyme 737460
Show all pathways known for 2.7.7.3Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.30.0000027 - methyl 4-[(3-[(1R)-2-cyano-1-[(5-methyl-1H-imidazo[4,5-b]pyridin-2-yl)amino]ethyl]phenyl)sulfanyl]piperidine-1-carboxylate pH 7.5, temperature not specified in the publication 761675
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