EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
2.7.10.2 | -999 |
- |
more |
- |
671253 |
2.7.10.2 | 0.00000023 |
- |
9-[(E)-2-(2,6-dimethylphenyl)ethenyl]-N-[4-(dimethylphosphoryl)phenyl]-2-(4-methylpiperazin-1-yl)-9H-purin-6-amine |
- |
691297 |
2.7.10.2 | 0.00000023 |
- |
9-[(E)-2-(2,6-dimethylphenyl)ethenyl]-N-[4-(dimethylphosphoryl)phenyl]-2-morpholin-4-yl-9H-purin-6-amine |
- |
691297 |
2.7.10.2 | 0.00000025 |
- |
INCB16562 |
JAK2 |
705895 |
2.7.10.2 | 0.0000003 |
- |
INCB20 |
TYK2, in 50 mM, Tris-HCl (pH 7.8), 100 mM NaCl, 5 mM dithiothreitol, and 0.1 mg/ml bovine serum albumin, at 25°C |
705664 |
2.7.10.2 | 0.00000046 |
- |
3-(9-[(E)-2-(2,6-dimethylphenyl)ethenyl]-6-[[4-(dimethylphosphoryl)phenyl]amino]-9H-purin-2-yl)propanenitrile |
- |
691297 |
2.7.10.2 | 0.00000046 |
- |
9-[(E)-2-(2,6-dimethylphenyl)ethenyl]-N-[4-(dimethylphosphoryl)phenyl]-2-(1-methylethoxy)-9H-purin-6-amine |
- |
691297 |
2.7.10.2 | 0.00000046 |
- |
9-[(E)-2-(2,6-dimethylphenyl)ethenyl]-N-[4-(dimethylphosphoryl)phenyl]-2-(1-methylpiperidin-4-yl)-9H-purin-6-amine |
- |
691297 |
2.7.10.2 | 0.00000046 |
- |
9-[(E)-2-(2,6-dimethylphenyl)ethenyl]-N-[4-(dimethylphosphoryl)phenyl]-2-(1H-imidazol-1-yl)-9H-purin-6-amine |
- |
691297 |
2.7.10.2 | 0.00000046 |
- |
9-[(E)-2-(2,6-dimethylphenyl)ethenyl]-N-[4-(dimethylphosphoryl)phenyl]-2-(2-methoxyethoxy)-9H-purin-6-amine |
- |
691297 |