EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
2.7.1.33 | 0.00006 |
- |
acetyl-CoA |
IC50: 60 nM, competitive inhibitor with respect to ATP |
676884 |
2.7.1.33 | 0.0000625 |
- |
acetyl-CoA |
- |
686741 |
2.7.1.33 | 0.00007 |
- |
N-[1-(5-[[2-(4-chlorophenoxy)ethyl]sulfanyl]-4-methyl-4H-1,2,4-triazol-3-yl)ethyl]naphthalene-1-carboxamide |
in 50 mM PIPES-NaOH (pH 7.0), 25 mM KCl, 20 mM MgCl, at 25°C |
722830 |
2.7.1.33 | 0.0001 |
- |
Fusidic acid |
isoform PanK3, at pH 7.5 and 37°C |
722018 |
2.7.1.33 | 0.000125 |
- |
acetyl-CoA |
- |
686741 |
2.7.1.33 | 0.00013 |
- |
N-(5-methoxypentyl)pantothenamide |
pH 7.6, 25°C |
758568 |
2.7.1.33 | 0.00024 |
- |
[2-[(3-chlorophenyl)sulfanyl]pyridin-4-yl][4-(hydroxymethyl)piperidin-1-yl]methanone |
in 50 mM PIPES-NaOH (pH 7.0), 25 mM KCl, 20 mM MgCl, at 25°C |
722830 |
2.7.1.33 | 0.0004 |
- |
1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea dihydrobromide |
isoform PanK3, at pH 7.5 and 37°C |
722018 |
2.7.1.33 | 0.0004 |
0.0016 |
pantothenamide, N-substituted |
IC50 about 0.0004-0.0016 mM |
641398 |
2.7.1.33 | 0.00042 |
- |
[2-[(3-chlorophenyl)sulfanyl]pyridin-4-yl][4-(hydroxymethyl)piperidin-1-yl]methanone |
in 50 mM PIPES-NaOH (pH 7.0), 25 mM KCl, 20 mM MgCl, at 25°C |
722830 |