EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
2.7.1.32 | -999 |
- |
more |
IC50 values for inhibitors with HepG2 cell and the cytosolic fraction of HepG2 cells, overview |
759713 |
2.7.1.32 | 0.00002 |
- |
(1S)-1-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-3-[2-[(oxan-4-yl)oxy]phenyl]-1-phenylpropan-1-ol |
pH 7.0, 25°C, recombinant enzyme |
759595 |
2.7.1.32 | 0.000066 |
- |
4,4'-bis((4-methyl-1,4-diazepan-1-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile |
at pH 7.0, temperature not specified in the publication |
738851 |
2.7.1.32 | 0.000066 |
- |
4,4'-bis((4-methyl-1,4-diazepan-1-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile |
pH 7.5, 25°C, recombinant enzyme |
759595 |
2.7.1.32 | 0.000085 |
- |
2'-fluoro-4,4'-bis((4-methyl-1,4-diazepan-1-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile |
at pH 7.0, temperature not specified in the publication |
738851 |
2.7.1.32 | 0.000085 |
- |
2'-fluoro-4,4'-bis((4-methyl-1,4-diazepan-1-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile |
pH 7.5, 25°C, recombinant enzyme |
759595 |
2.7.1.32 | 0.0001 |
- |
MN58b |
H510 cell, 144 h |
688743 |
2.7.1.32 | 0.000165 |
- |
4,4'-((2-fluoro-[1,1'-biphenyl]-4,4'-diyl)bis(methylene))bis(1-methyl-1,4-diazepane) |
at pH 7.0, temperature not specified in the publication |
738851 |
2.7.1.32 | 0.000165 |
- |
4,4'-((2-fluoro-[1,1'-biphenyl]-4,4'-diyl)bis(methylene))bis(1-methyl-1,4-diazepane) |
pH 7.5, 25°C, recombinant enzyme |
759595 |
2.7.1.32 | 0.000233 |
- |
4,4'-((2,3-difluoro-[1,1'-biphenyl]-4,4'-diyl)bis(methylene))bis-(1-methyl-1,4-diazepane) |
at pH 7.0, temperature not specified in the publication |
738851 |