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EC Number	IC50 Value	IC50 Value Maximum	Inhibitor	Commentary	Reference
2.4.2.14	-999	-	DAS734	20-35 microM leads to 50% inhibition of Arabidopsis root growth (RI50) at in presence of endogenous AtGPRAT2 harbouring R264K polymorphism	694707
2.4.2.14	-999	-	DAS734	200 nM leads to 50% inhibition of Arabidopsis root growth (RI50) in wild-type AtGPRAT2 expressing seedlings	694707
2.4.2.14	-999	-	DAS734	>500-fold higher for mutant R264K compared to wild-type	694707
2.4.2.14	0.0002	-	DAS734	10 min preincubation of recombinant enzyme with inhibitor leads to maximum inhibition, slow but reversible binding	694707
2.4.2.14	0.0002	-	DAS734	cell extracts of recombinant AtGPRAT3 expressing Escherichia coli	694707
2.4.2.14	0.4	-	5',5'-P1,P4-diguanosine tetraphosphate	IC50: 0.4 mM, 2 mM, approx. 80% inhibition	489750
2.4.2.14	7.9	-	GMP	IC50: 7.9 mM	489772

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Release 2023.1 (January 2023)