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Results 1 - 7 of 7
EC Number IC50 Value IC50 Value Maximum Inhibitor Commentary Reference
Show all pathways known for 2.3.1.179Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.179-999 - more IC50 for platencin is 0.00195 ng/ml, IC50 for platensimycin is 0.00013 ng/ml 676903
Show all pathways known for 2.3.1.179Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.1790.000048 - platensimycin from Streptomyces platensis, IC50: 48 nM, anti-bacterial effect is exerted through the selective targeting of beta-ketoacyl-[acyl-carrier-protein] synthase I/II, FabF/B, in the synthetic pathway of fatty acids, platensimycin interacts specifically with th 676148
Show all pathways known for 2.3.1.179Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.1790.000097 - dihydroplatensimycin IC50: 97 nM 676148
Show all pathways known for 2.3.1.179Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.1790.000113 - platencin exhibits a broad-spectrum Gram-positive antibacterial activity through inhibition of fatty acid biosynthesis, targets the two essential proteins, beta-ketoacyl-[acyl carrier protein] synthase II and III, i.e. FabF and FabH, FabF IC50: 113 nM, overview 676903
Show all pathways known for 2.3.1.179Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.1790.00016 - platensimycin from Streptomyces platensis, IC50: 160 nM, anti-bacterial effect is exerted through the selective targeting of beta-ketoacyl-[acyl-carrier-protein] synthase I/II, FabF/B, in the synthetic pathway of fatty acids, platensimycin interacts specifically with t 676148
Show all pathways known for 2.3.1.179Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.1790.00029 - platensimycin from a strain of Streptomyces platensis MA7339, specifically targets FabF, IC50: 290 nM, exhibits Gram-positive antibacterial activity 676903
Show all pathways known for 2.3.1.179Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.1791.1 - thiolactomycin binding structure with mutant C163Q, IC50: 1.1 mM 676148
Results 1 - 7 of 7