EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
    1.3.1.72 | 0.0000001 |
- |
(3S,20S)-20-(hydroxymethyl)-pregn-7-en-3-ol |
at 37°C, pH not specified in the publication |
764619 |
| 1.3.1.72 | 0.0000025 |
- |
(7S,9aR,11aS)-1-[(2S)-1-hydroxypropan-2-yl]-9a,11a-dimethyl-2,3,3a,3b,4,6,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[a]phenanthren-7-ol |
at 37°C, pH not specified in the publication |
764619 |
| 1.3.1.72 | 0.0000029 |
- |
(1R,3aR,5aS,7S,9aS,9bR,11aR)-9a,11a-dimethyl-1-[(2R,3E)-4-phenylbut-3-en-2-yl]-2,3,3a,5,5a,6,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[a]phenanthren-7-ol |
at 37°C, pH not specified in the publication |
764619 |
| 1.3.1.72 | 0.0000033 |
- |
(7S,9aS,11aR)-1-[(2S)-1-hydroxypropan-2-yl]-9a,11a-dimethyl-2,3,3a,5,5a,6,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[a]phenanthren-7-yl acetate |
at 37°C, pH not specified in the publication |
764619 |
| 1.3.1.72 | 0.0000042 |
- |
(3S,20S)-20-[(formyloxy)methyl]-pregn-7-en-3-yl acetate |
at 37°C, pH not specified in the publication |
764619 |
| 1.3.1.72 | 0.000005 |
- |
SH42 |
pH and temperature not specified in the publication |
765679 |
| 1.3.1.72 | 0.0000055 |
- |
(3S,20S)-20-[(dimethylamino)acetoxymethyl]-pregn-7-en-3-yl acetate |
at 37°C, pH not specified in the publication |
764619 |
| 1.3.1.72 | 0.0000063 |
- |
(3S,20S)-20-[((E)-but-2-enoyloxy)methyl]-pregn-7-en-3-yl acetate |
at 37°C, pH not specified in the publication |
764619 |
| 1.3.1.72 | 0.00015 |
- |
3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-one |
U18666A, non-competitive inhibition, Ki: 0.000157 mM, IC50 about 0.00015 mM, 690fold higher affinity for the enzyme than substrate lanosterol |
288496 |
| 1.3.1.72 | 0.000198 |
- |
(3S,20S)-20-(aminomethyl)-pregn-7-en-3-yl acetate |
at 37°C, pH not specified in the publication |
764619 |
