EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
   1.1.1.50 | 0.000049 |
- |
ursodeoxycholate |
natural inhibitor, in vivo IC50: 0.00024 mM in fluorometric assay, 0.00014 mM in radiometric assay, in vitro IC50: 0.000049 mM in fluorometric assay |
676812 |
| 1.1.1.50 | 0.00031 |
- |
Flufenamic acid |
synthetic, nonsteroidal anti-inflammatory inhibitor, in vivo IC50: 0.0040 mM in fluorometric assay, in vitro IC50: 0.00031 mM in fluorometric assay |
676812 |
| 1.1.1.50 | 0.0004 |
- |
Phenolphthalein |
AKR1C4-selective inhibitor, in vitro and in vivo inhibition, IC50: 0.0004 mM |
675595 |
| 1.1.1.50 | 0.000891 |
- |
apigenin |
37°C, pH 7.2 |
762009 |
| 1.1.1.50 | 0.0027 |
- |
naproxen |
synthetic, nonsteroidal anti-inflammatory inhibitor, in vivo IC50: 0.0094 mM in fluorometric assay, 0.016 mM in radiometric assay, in vitro IC50: 0.0027 mM in fluorometric assay |
676812 |
| 1.1.1.50 | 0.0034 |
- |
NADH |
wild-type, pH 7.5, 25°C |
711310 |
| 1.1.1.50 | 0.004 |
- |
NADH |
mutant Y155F, pH 7.5, 25°C |
711310 |
| 1.1.1.50 | 0.0058 |
- |
tert-butyl-4-hydroxyanisole |
37°C, pH not specified in the publication |
762014 |
| 1.1.1.50 | 0.009 |
- |
Ibuprofen |
synthetic, nonsteroidal anti-inflammatory inhibitor, in vivo IC50: 0.017 mM in fluorometric assay, in vitro IC50: 0.009 mM in fluorometric assay |
676812 |
| 1.1.1.50 | 0.01 |
- |
NADH |
mutant N86A, pH 7.5, 25°C |
711310 |
