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EC Number Crystallization (Commentary)
Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.18A 2.18 A resolution X-ray crystal structure of the inactivated complex elucidates the orientation of the inactivator and its covalent attachment to the active site Cys
Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.18by sitting drop vapor diffusion, at 1.08-2.0 A resolution and at pH 6.3 and pH 9.0
Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.18N5-(1-iminopropyl)-L-ornithine:DDAH-1 complex, to 1.9 A resolution, covalent bond formation between the inhibitor’s amidino carbon and the active-site Cys274, and solution studies show reversible competitive inhibition, consistent with a reversible covalent mode of DDAH inhibition by alkylamidine inhibitors
Results 1 - 3 of 3