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EC Number Crystallization (Commentary)
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B10-
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B10crystal structures of the APPIWT/KLK6 and APPI-4M/KLK6 complexes reveal the structural and mechanistic bases for the improved KLK6 binding and proteolytic resistance of APPI-4M. APPI is the amyloid precursor protein Kunitz protease inhibitor domain. APPI-4M i.e. APPI(M17L/I18F/S19F/F34V)
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B10purified enzyme bound to inhibitor 9b, X-ray diffraction structure determination and analysis at 1.68 A resolution
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