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EC Number Crystallization (Commentary)
Display the word mapDisplay the reaction diagram Show all sequences 3.1.6.13structural models of the wild type and mutant IDS proteins resulting from 131 missense mutations identified in patients with mucopolysaccharidosis MPS II. The amino acid substitutions causing MPS II are widely spread over the enzyme molecule and the structural changes of the enzyme protein are generally larger in the severe group than in the attenuated one. The structural changes influence the disease progression
Display the word mapDisplay the reaction diagram Show all sequences 3.1.6.13structure with a covalently bound sulfate ion in the active site, to 2.3 A resolution
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