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Crystallization (Commentary)
Reference
3.1.2.28
to 1.9 A resolution. The core structure is defined by a 5-6-stranded antiparallel beta-sheet that partially wraps around a prominent five-turn alpha-helix. Isoform DHNAT1 has a 27-amino-acid extension at its N-terminus. DHNAT1 is a facial tetramer that features a dimer-dimer interface near the hotdog alpha-helices, which point inward towards the center of the tetramer. The binding site for substrate 1,4-dihydroxy-2-naphthoyl-CoA spans the dimer interface
728870
3.1.2.28
to 1.9 A resolution. The core structure is defined by a 5-6-stranded antiparallel beta-sheet that partially wraps around a prominent five-turn alpha-helix. Isoform Slr0204 has a 25-amino-acid extension at its C-terminus, residues 113-138. Slr0204 is a facial tetramer that features a dimer-dimer interface near the hotdog alpha-helices, which point inward towards the center of the tetramer. The binding site for substrate 1,4-dihydroxy-2-naphthoyl-CoA spans the dimer interface
728870
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