EC Number   |
Reference |
|---|
   3.1.1.7 | - |
114161, 114174, 114175, 114183, 729173 |
| 3.1.1.7 | analysis of crystal structure PDB ID 4ey4 |
743326 |
| 3.1.1.7 | complex with rivastigmine or (-)-S-3-[1-(dimethylamino)ethyl]phenol, hanging drop vapor diffusion method |
650141 |
| 3.1.1.7 | complexed with (-)-huperzine B and (+)-huperzine A |
650098 |
| 3.1.1.7 | crystal structure analysis, overview |
693706 |
| 3.1.1.7 | enzyme in complex with inhibitors (2E)-2-[(1-benzylpiperidin-4-yl)methylidene]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one and (2E)-2-[(1-benzylpiperidin-4-yl)methylidene]-5-methoxy-2,3-dihydro-1H-inden-1-one, ligands dissolved in 100 mM DMSO, soaking of native crystals at 4°C for 24 h, in a solution containing 2 mM (2E)-2-[(1-benzylpiperidin-4-yl)methylidene]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one or (2E)-2-[(1-benzylpiperidin-4-yl)methylidene]-5-methoxy-2,3-dihydro-1H-inden-1-one, 30% PEG 200, 8% DMSO, and 100 mM MES at pH 6.2, X-ray diffraction structure determination and analysis at 2.17.A and 2.25 A resolution, respectively |
751215 |
| 3.1.1.7 | enzyme in complex with inhibitors, nerve agents and organophosphorous-based insecticides, in aged and non-aged forms, the non-aged complexes are generated by crystal soaking methods, by slow equilibration of crystals in X-buffer composed of 28% v/v PEG monomethyl ether 750, and 100 mM HEPES, pH 7.0, prior to data collection, X-buffer is supplemented with the appropriate organophosphorous compound at a concentration of 10 mM for sarin, VX, and diisopropyl fluorophosphate and 100 mM for methamidophos and fenamifos, the solution is subsequently added to the equilibrated crystals in several portions during different periods, aged forms establish during several weeks, X-ray diffraction structure determination and anaylsis at 2.5-2.9 A resolution, modelling |
678274 |
| 3.1.1.7 | in complex with aflatoxin |
716858 |
| 3.1.1.7 | in complex with tabun, prior and after intramolecular dealkylation or deamidation reaction caused by tabun and called aging. Nonaged tabun conjugate induces a structural change at H447 that uncouples the catalytic triad. In aged tabun conjugate, side chains of H447 and F338 are reversed to the conformation of the apo structure of enzyme |
664138 |
| 3.1.1.7 | native enzyme by hanging-drop vapour diffusion method, 4°C, 11.5 mg/ml protein, mother liquor is 32% PEG 200 in 0.15 M MES, pH 5.8-6.2, soaking of crystals at 4°C in mother liquor at pH 6.0, containing either 0.5 mM OTMA for 24 h in 5 ml soaking solution, 20 mM TCh for 12 h in 5 ml soaking solution, 500 mM ATCh for 40 min in 1.5 ml soaking solution, or 20 mM ATCh for 12 h in 200 ml soaking solution, X-ray diffraction structure determination and anaylsis at 2.0-2.7 A resolution |
679488 |
